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Table 1 Baseline characteristics of patients with stage IA NSCLC ≤ 2 cm in size stratified by NLNs without and with PSM

From: Association between number of dissected lymph nodes and survival in stage IA non-small cell lung cancer: a propensity score matching analysis

 

Without PSM

With PSM

Groups

NLNs ≤ 5

NLNs > 5

p value

NLNs ≤ 5

NLNs > 5

p value

Total

3850

3443

 

2350

2350

 

Sex (%)

  

0.437*

  

0.423*

 Male

1588 (41.2%)

1452 (42.2%)

 

968 (41.2%)

940 (40.0%)

 

 Female

2262 (58.8%)

1991 (57.8%)

 

1382 (58.8%)

1410 (60.0%)

 

Age (%)

  

< 0.001*

  

0.906*

 ≤ 65

1468 (38.1%)

1517 (44.1%)

 

990 (42.1%)

985 (41.9%)

 

 > 65

2382 (61.9%)

1926 (55.9%)

 

1360 (57.9%)

1365 (58.1%)

 

TNM stage (%)

  

0.004*

  

1*

 IA1

703 (18.3%)

541 (15.7%)

 

349 (14.9%)

350 (14.9)

 

 IA2

3147 (81.7%)

2902 (84.3%)

 

2001 (85.1%)

2000 (85.1%)

 

Grade (%)

  

< 0.001*

  

0.707*

 I

841 (21.8%)

774 (22.5%)

 

525 (22.3%)

530 (22.6%)

 

 II

1622 (42.1%)

1569 (45.6%)

 

1045 (44.5%)

999 (42.5%)

 

 III

992 (25.8%)

847 (24.6%)

 

578 (24.6%)

609 (25.9%)

 

 IV

55 (1.4%)

37 (1.1%)

 

32 (1.4%)

32 (1.4%)

 

 Unknown

340 (8.8%)

216 (6.3%)

 

170 (7.2%)

180 (7.7%)

 

Tumor location (%)

  

< 0.001**

  

1**

 Upper lobe

2258 (58.6%)

2289 (66.5%)

 

1388 (59.1%)

1395 (59.4%)

 

 Middle lobe`

311 (8.1%)

148 (4.3%)

 

148 (6.3%)

146 (6.2%)

 

 Lower lobe

1216 (31.6%)

965 (28.0%)

 

783 (33.3%)

777 (33.1%)

 

 Main bronchus

5 (0.1%)

4 (0.1%)

 

1 (0.0%)

1 (0.0%)

 

 Overlapping

16 (0.4%)

12 (0.3%)

 

10 (0.4%)

10 (0.4%)

 

 Lung NOS

44 (1.1%)

25 (0.7%)

 

20 (0.9%)

21 (0.9%)

 

Tumor size (mean (SD) (mm))

14.72 (4.03)

15.05 (3.86)

< 0.001***

15.12 (3.88)

15.08 (3.81)

0.690***

Race (%)

  

0.059**

  

0.972**

 American Indian

15 (0.4%)

14 (0.4%)

 

10 (0.4%)

12 (0.5%)

 

 Asian

194 (5.0%)

203 (5.9%)

 

141 (6.0%)

148 (6.3%)

 

 Black

324 (8.4%)

239 (6.9%)

 

197 (8.4%)

196 (8.3%)

 

 White

3308 (85.9%)

2983 (86.6%)

 

3 (0.1%)

4 (0.2%)

 

 Unknown

9 (0.2%)

4 (0.1%)

 

1999 (85.1%)

1990 (84.7%)

 

Surgical methods (%)

  

< 0.001**

  

1**

 Wedge resection

1417 (36.8%)

230 (6.7%)

 

230 (9.8%)

230 (9.8%)

 

 Segmental resection

284 (7.4%)

80 (2.3%)

 

79 (3.4%)

79 (3.4%)

 

 Lobectomy

2126 (55.2%)

3102 (90.1%)

 

2030 (86.4%)

2030 (86.4%)

 

 Pneumonectomy

17 (0.4%)

28 (0.8%)

 

11 (0.5%)

11 (0.5%)

 

 Unknown

6 (0.2%)

3 (0.1%)

 

0 (0.0%)

0 (0.0%)

 

Histological types (%)

  

0.157**

  

0.866**

 Adeno

2503 (65.0%)

2297 (66.7%)

 

1592 (67.7%)

1565 (66.6%)

 

 SCC

861 (22.4%)

745 (21.6%)

 

494 (21.0%)

510 (21.7%)

 

 LCC

117 (3.0%)

74 (2.1%)

 

56 (2.4%)

60 (2.6%)

 

 PSC

3 (0.1%)

2 (0.1%)

 

1 (0.0%)

0 (0.0%)

 

 Other

222 (5.8%)

210 (6.1%)

 

134 (5.7%)

136 (5.8%)

 

 Unknown

144 (3.7%)

115 (3.3%)

 

73 (3.1%)

79 (3.4%)

 
  1. NSCLC non-small cell lung cancer, NLNs the number of removed lymph nodes, PSM propensity score matching, Lung NOS uncertain location on lung, Adeno adenocarcinoma, SCC squamous cell carcinoma, LCC large cell carcinoma, PSC pulmonary sarcomatoid carcinoma, Other other histological types
  2. *Chi-squared test
  3. **Fisher’s exact test
  4. ***Student’s t test