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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: PD-1/PD-L1 expression profiles within intrahepatic cholangiocarcinoma predict clinical outcome

Fig. 2

Different expression patterns of PD-1 in CTLs in ICC tumors. a Representative multiplex immunofluorescence staining to reveal different expression level of PD1 on both CD8 in tumor tissues (T) and peri-tumor tissues (P): red arrows (CD8+ PD-1High); yellow arrows (CD8+ PD-1Low). Scale bar, 50 μm. High expression and low expression in CTLs in tumor tissue were observed by double color staining.

b Quantitative comparisons analysis of CD8+ PD-1High cells and CD8+ PD-1Low cells in between the paired tumor tissues (T) and peri-tumor tissues (P) (Wilcoxon signed-rank test)

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