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Fig. 3 | World Journal of Surgical Oncology

Fig. 3

From: Proline-rich protein 11 overexpression is associated with a more aggressive phenotype and poor overall survival in ovarian cancer patients

Fig. 3

Knockdown of PRR11 expression inhibited the proliferation and migration of OC cells in vitro and in vivo. a Western blot and b qPCR analysis showing expression levels of the PRR11 protein in HO8910 and SKOV3 human OC cells after stable infection with shPRR11 viruses. c Relative cell viability of cancer cells after PRR11-knockdown. d Representative pictures of the cell migration assay and e graphical presentation of the number of migrating cells 16-h post-transfection. f Pictures of tumors resected from subcutaneous tumor xenograft models and g tumor volume. h Ki67 staining in tumor sections. *P < 0.05, **P < 0.01, compared with the control group

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