|
Variable
|
Open (N = 149)
|
Laparoscopy (N = 300)
|
p value
|
|---|
|
Age (years)
|
64.9 ± 12.8
|
63.6 ± 12.6
|
0.298a
|
|
Gender
|
Male
|
82 (55.0)
|
172 (57.3)
|
0.643c
|
|
Female
|
67 (45.0)
|
128 (42.7)
|
|
BMI (kg/m2)
|
22.0 ± 3.3
|
23.7 ± 3.5
|
< .001a
|
|
ASA score
|
1, 2
|
128 (85.9)
|
288 (96)
|
< .001c
|
|
3, 4
|
21 (14.1)
|
12 (4)
|
|
Preoperative CEA (ng/ml)
|
3.3 (0.5–338)
|
4.3 (0.4–543)
|
0.126b
|
|
Location
|
Right
|
64 (43.0)
|
142 (47.3)
|
0.380c
|
|
Left
|
85 (57.0)
|
158 (52.7)
|
|
Operative time (min)
|
141 (43–520)
|
160 (50–460)
|
0.007b
|
|
Blood loss (ml)
|
100 (0–4000)
|
50 (0–700)
|
< .001b
|
|
Transfusion
|
No
|
130 (87.3)
|
298 (99.3)
|
< .001d
|
|
Yes
|
19 (12.8)
|
2 (0.7)
|
|
Hospital stay (days)
|
10 (5–45)
|
8 (4–158)
|
< .001b
|
|
Postoperative morbidity
|
No
|
105 (70.5)
|
246 (82.0)
|
0.005c
|
|
Yes
|
44 (29.5)
|
54 (18.0)
|
|
Postoperative morbidity type
|
Ileus
|
7 (15.9)
|
15 (27.8)
| |
|
Urinary retention
|
2 (4.6)
|
5 (9.3)
| |
|
Anastomotic leakage
|
0 (0)
|
3 (5.6)
| |
|
Surgical site infection
|
17 (38.6)
|
15 (27.8)
| |
|
Pneumonia
|
5 (11.4)
|
2 (3.7)
| |
|
Sepsis
|
3 (6.8)
|
3 (5.6)
| |
|
Others
|
10 (22.7)
|
11 (20.4)
| |
|
Clavien–Dindo classification
|
1, 2
|
34 (77.3)
|
42 (77.8)
|
0.953c
|
|
3
|
10 (22.7)
|
12 (22.2)
|
|
Adjuvant chemotherapy (N = 329)
|
No
|
20 (28.6)
|
39 (15.1)
|
0.009 c
|
|
Yes
|
50 (71.4)
|
220 (78.7)
|
- aTwo-sample t test
- bWilcoxon rank sum test
- cChi-square test
- dFisher’s exact test
- Data are expressed as mean ± standard deviation or median (range) for continuous variables and as number (percentage) for categorical variables
- ASA American Society of Anesthesiologists, BMI body mass index, CEA carcinoembryonic antigen
