Favorable short-term oncologic outcomes following laparoscopic surgery for small T4 colon cancer: a multicenter comparative study

Table 1 Patient characteristics and perioperative outcomes

Variable		Open (N = 149)	Laparoscopy (N = 300)	p value
Age (years)		64.9 ± 12.8	63.6 ± 12.6	0.298^a
Gender	Male	82 (55.0)	172 (57.3)	0.643^c
Gender	Female	67 (45.0)	128 (42.7)	0.643^c
BMI (kg/m²)		22.0 ± 3.3	23.7 ± 3.5	< .001^a
ASA score	1, 2	128 (85.9)	288 (96)	< .001^c
ASA score	3, 4	21 (14.1)	12 (4)	< .001^c
Preoperative CEA (ng/ml)		3.3 (0.5–338)	4.3 (0.4–543)	0.126^b
Location	Right	64 (43.0)	142 (47.3)	0.380^c
Location	Left	85 (57.0)	158 (52.7)	0.380^c
Operative time (min)		141 (43–520)	160 (50–460)	0.007^b
Blood loss (ml)		100 (0–4000)	50 (0–700)	< .001^b
Transfusion	No	130 (87.3)	298 (99.3)	< .001^d
Transfusion	Yes	19 (12.8)	2 (0.7)	< .001^d
Hospital stay (days)		10 (5–45)	8 (4–158)	< .001^b
Postoperative morbidity	No	105 (70.5)	246 (82.0)	0.005^c
Postoperative morbidity	Yes	44 (29.5)	54 (18.0)	0.005^c
Postoperative morbidity type	Ileus	7 (15.9)	15 (27.8)
	Urinary retention	2 (4.6)	5 (9.3)
	Anastomotic leakage	0 (0)	3 (5.6)
	Surgical site infection	17 (38.6)	15 (27.8)
	Pneumonia	5 (11.4)	2 (3.7)
	Sepsis	3 (6.8)	3 (5.6)
	Others	10 (22.7)	11 (20.4)
Clavien–Dindo classification	1, 2	34 (77.3)	42 (77.8)	0.953^c
Clavien–Dindo classification	3	10 (22.7)	12 (22.2)	0.953^c
Adjuvant chemotherapy (N = 329)	No	20 (28.6)	39 (15.1)	0.009 ^c
Adjuvant chemotherapy (N = 329)	Yes	50 (71.4)	220 (78.7)	0.009 ^c

^aTwo-sample t test
^bWilcoxon rank sum test
^cChi-square test
^dFisher’s exact test
Data are expressed as mean ± standard deviation or median (range) for continuous variables and as number (percentage) for categorical variables
ASA American Society of Anesthesiologists, BMI body mass index, CEA carcinoembryonic antigen

ISSN: 1477-7819