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Table 1 The perioperative treatment and postoperative outcome parameters

From: Perioperative strategy and outcome in giant retroperitoneal dedifferentiated liposarcoma—results of a retrospective cohort study

Parameter

Variable

Value (n)

Gender

Female

5

Male

5

Age

Years, median (range)

58 (40–76)

Radiochemotherapy

Neoadjuvant (with additional hyperthermia)

6 (1)

Adjuvant

0

None

4

Chemotherapy

Adjuvant

1

None

3

Origin

Retroperitoneal

 Left

4

 Right

6

Operative procedures performed

Laparotomy, midline

10

 En bloc compartmental resection + 0 organs

2

 En bloc compartmental resections + 1 organ

3

 En bloc compartmental resections + 2 organs

4

 En bloc compartmental resections + 3 organs

1

Resected organs

Kidney

4

Intestine, large

6

Adrenal gland

2

Orchiectomy

2

Operation time

Minutes, median (range)

253 (165–458)

Specific perioperative complications:

Major

2

 Necessitating laparotomy

2

 Anastomotic insufficiency bowel

1

Minor

2

 Urinary tract infection (Candida)

1

 Diarrhea (C. difficile)

1

Hospital stay

Duration (days)

15.2 (11–21)

Pathologic dimension

Median

360 (300–440)

> 300 and < 350 mm

4

> 350 and < 400 mm

4

> 400 mm

2

Surgical margins

Wide (R0)

3

Marginal (R1)

7

Intralesional (R2)

0

Histology

Dedifferentiated

10 (100%)

Tumor response

Radiologic (RECIST)

 Regressive

0

 Stable

6 (100%)

 Progressive

0

Histologic (% tumor vitality)

 < 20

0

 20–30

1

 30–60

3

 60–90

2

 > 90

0

Tumor relapse

Site of recurrence

 Local

3

 Local metastatic (abdominal/peritoneal)

2

 Metastatic (pulmonal/cerebral)

1