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Table 1 Clinic-pathological characteristics and the univariate and multivariate survival analysis in gastric cancer patients and in patients with GBAI or not

From: Cancer cells invasion to the gastric bare area adipose tissue: a poor prognostic predictor for gastric cancer

Variables n (%) 5-year survival rate (%) P HR (95% CI) P Non-GBAI (%) GBAI P HR (95% CI) P
Gender
 Female 602 (33.0) 60.0 0.580    534 (33.0) 68 (33.2) 0.883   
 Male 1220 (67.0) 61.3    1083 (67.0) 137 (66.8)   
Age (years)
 < 50 478 (26.2) 66.3 0.004 ref.   432 (26.7) 46 (22.4) 0.176   
 ≥ 50 1244 (73.8) 58.9 1.02 (1.01–1.03) < 0.001 1185 (73.3) 159 (77.6)   
Tumor size (cm)
 ≤ 5.0 1210 (66.4) 66.5 < 0.001 ref.   1112 (68.8) 98 (47.8) < 0.001 ref.  
 > 5.0 612 (33.6) 49.7 1.03 (0.89–1.20) 0.668 505 (31.2) 107 (52.2) 1.08 (0.87–1.33) 0.304
Tumor site
 Distal 1006 (55.2) 70.3 < 0.001 ref.   954 (59.0) 52 (25.4) < 0.001 ref.  
 Proximal/linitis lastica 816 (44.8) 49.3 1.43 (1.23–1.68) < 0.001 663 (41.0) 153 (74.6) 1.63 (1.40–1.90) < 0.001
Histological grade
 Well/moderately differentiated 262 (14.4) 69.5 0.234    247 (15.3) 15 (7.3) 0.009 ref.  
 Poorly differentiated 1197 (65.7) 58.3    1054 (65.2) 143 (69.8) 1.18 (0.93–1.51) 0.174
 Undifferentiated/signet ring cell carcinoma 363 (19.9) 63.1    316 (19.5) 47 (22.9) 1.16 (0.87–1.54) 0.309
Vascular invasion
 No 1529 (83.9) 62.9 < 0.001 ref.   1396 (86.3) 133 (64.9) < 0.001 ref.  
 Yes 293 (16.1) 50.5 0.883 (0.72–1.08) 0.217 221 (13.7) 72 (35.1) 1.07 (0.87–1.33) 0.506
Nerve invasion
 No 1465 (80.4) 60.8 0.932    1348 (83.4) 117 (57.1) < 0.001 ref.  
 Yes 357 (19.6) 61.1    269 (16.6) 88 (42.9) 0.86 (0.69–1.06) 0.152
Adipose tissues invasion
 No 1437 (78.9) 67.6 < 0.001 ref.       
 Yes 385 (21.1) 35.6 1.31 (1.05–1.65) 0.019      
GBAI
 No 1617 (88.7) 63.1 < 0.001 ref.       
 Yes 205 (11.3) 19.6 1.45 (1.12–1.89) 0.005      
Depth of invasion
 T1 235 (12.9) 96.2 < 0.001 ref.   235 (14.5) 0 (0.0) < 0.001 ref.  
 T2 217 (11.9) 83.4 3.35 (1.61–7.98) 0.001 215 (13.3) 2 (1.0) 3.36 (1.61–7.00) 0.001
 T3 421 (23.1) 64.4 5.94 (2.99–11.80) < 0.001 377 (23.3) 44 (21.5) 6.66 (3.35–13.25) < 0.001
 T4a 892 (49.0) 45.9 8.46 (4.30–16.63) < 0.001 744 (46.0) 148 (72.2) 9.33 (4.75–18.31) < 0.001
 T4b 57 (3.1) 38.6 10.49 (4.95–22.22) < 0.001 46 (2.8) 11 (5.4) 10.97 (5.18–23.24) < 0.001
Nodal status
 N0 561 (30.8) 80.6 < 0.001 ref.   551 (34.0) 10 (4.9) < 0.001 ref.  
 N1 289 (15.9) 74.7 1.08 (0.80–1.46) 0.612 272 (16.8) 17 (8.3) 1.14 (0.84–1.53) 0.400
 N2 306 (16.8) 61.1 1.54 (1.18–2.01) 0.001 273 (16.9) 33 (16.1) 1.61 (1.23–2.10) < 0.001
 N3a 402 (22.1) 46.8 2.41 (1.89–3.01) < 0.001 336 (20.8) 66 (32.2) 2.49 (1.96–3.17) < 0.001
 N3b 264 (14.5) 25.0 3.95 (3.04–5.14) < 0.001 185 (11.4) 79 (38.5) 4.23 (3.27–5.47) < 0.001