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Table 3 Univariate and multivariate analyses of factors predicting disease-free survival

From: The preoperative and the postoperative neutrophil-to-lymphocyte ratios both predict prognosis in gastric cancer patients

  Univariate analysis Multivariate analysis
HR (95% CI) P value Adjusted HRa (95% CI) P value
Preoperative NLR
 LNLR (NLR < 2) Reference   Reference  
 HNLR (NLR ≥ 2) 1.829 (1.337-2.503) 0.000 1.319 (0.929-1.873) 0.122
Postoperative NLR
 LNLR (NLR < 1.7) Reference   Reference  
 HNLR (NLR ≥ 1.7) 1.224 (0.853-1.757) 0.273 1.136 (0.775-1.664) 0.513
NLR change
 LL (preoperative NLR < 2, postoperative NLR < 1.7) Reference   Reference  
 LH (preoperative NLR < 2, postoperative NLR ≥1.7) 0.795 (0.377-1.676) 0.546 0.764 (0.356-1.642) 0.491
 HL (preoperative NLR ≥ 2, postoperative NLR < 1.7) 1.806 (1.201-2.715) 0.005 1.168 (0.765-1.783) 0.472
 HH (preoperative NLR ≥ 2, postoperative NLR ≥ 1.7) 1.955 (1.269-3.011) 0.002 1.400 (0.892-2.197) 0.143
  1. HR hazard ratio, CI confidence interval, NLR neutrophil-to-lymphocyte ratio, LNLR low NLR, HNLR high NLR, LL low to low, LH low to high, HL high to low, HH high to high
  2. aAdjusted for age, approach method, extent of resection, depth of invasion, node status, stage, and adjuvant chemotherapy