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Table 2 Univariate and multivariate analyses of factors predicting overall survival

From: The preoperative and the postoperative neutrophil-to-lymphocyte ratios both predict prognosis in gastric cancer patients

  Univariate analysis Multivariate analysis
HR (95% CI) P value Adjusted HRa (95% CI) P value
Preoperative NLR
 LNLR (NLR < 2) Reference   Reference  
 HNLR (NLR ≥ 2) 1.719 (1.306-2.262) 0.000 1.449 (1.048-2.004) 0.025
Postoperative NLR
 LNLR (NLR < 1.7) Reference   Reference  
 HNLR (NLR ≥ 1.7) 1.946 (1.410-2.686) 0.000 1.556 (1.112-2.176) 0.010
NLR change
 LL (preoperative NLR < 2, postoperative NLR < 1.7) Reference   Reference  
 LH (preoperative NLR < 2, postoperative NLR ≥ 1.7) 1.403 (0.791-2.490) 0.247 1.040 (0.575-1.882) 0.896
 HL (preoperative NLR ≥ 2, postoperative NLR < 1.7) 1.370 (0.894-2.100) 0.148 1.070 (0.692-1.655) 0.761
 HH (preoperative NLR ≥ 2, postoperative NLR ≥ 1.7) 2.600 (1.763-3.834) < 0.001 1.817 (1.220-2.706) 0.003
  1. HR hazard ratio, CI confidence interval, NLR neutrophil-to-lymphocyte ratio, LNLR low NLR, HNLR high NLR
  2. aAdjusted for age, approach method, extent of resection, depth of invasion, node status, stage, and adjuvant chemotherapy