Table 4 Comparison of intraoperative factors and postoperative short-term and long-term results after PS matching
Variable | Aged < 70 years (n = 128) | Aged ≥ 70 years (n = 64) | P value | Standardized mean difference |
|---|---|---|---|---|
Combined with RFA | 1 (0.8%) | 3 (4.7%) | 0.109 | 0.043 |
Two-stage hepatectomy | 1 (0.8%) | 1 (1.6%) | 1.000 | |
Simultaneous resection | 17 (13.3%) | 16 (25.0%) | 0.066 | |
Major hepatectomy | 24 (18.8%) | 8 (12.5%) | 0.273 | 0.023 |
Pringle clamp | 95 (74.2%) | 44 (68.8%) | 0.424 | |
Pringle clamp time (min) | 15 (0–60) | 15 (0–60) | 0.465 | |
R1 margin | 3 (2.3%) | 6 (9.4%) | 0.062 | |
Intraoperative blood loss (ml) | 200 (20–6500) | 175 (20–800) | 0.046 | |
Intraoperative RBC transfusion | 10 (7.9%) | 3 (4.7%) | 0.549 | |
Intraoperative RBC transfused (U) | 0 (0–8) | 0 (0–4) | 0.313 | |
Operation time (min) | 172.5 (60–570) | 180 (60–327) | 0.799 | |
Hospital stay (days) | 11 (4–70) | 8 (4–48) | 0.020 | |
Postoperative complications | 37 (28.9%) | 17 (26.6%) | 0.733 | |
Clavien-Dindo classification | 0.062 | |||
I–II | 16 (43.2%) | 12 (70.6%) | ||
III–V | 21 (56.8%) | 5 (29.4%) | ||
General complications | 15 (11.7%) | 4 (6.3%) | 0.232 | |
Postoperative heart failure | 0 (0.0%) | 0 (0%) | - | |
Postoperative coronary artery disease | 2 (1.6%) | 0 (0%) | 0.553 | |
Postoperative arrhythmia | 0 (0.0%) | 1 (1.6%) | 0.333 | |
Postoperative lung infection | 1 (0.8%) | 1 (1.6%) | 1.000 | |
Postoperative renal failure | 0 (0.0%) | 0 (0.0%) | - | |
Postoperative pulmonary embolism | 1 (0.8%) | 0 (0.0%) | 1.000 | |
Postoperative deep vein thrombosis | 0 (0.0%) | 0 (0.0%) | - | |
Postoperative urinary infection | 0 (0.0%) | 0 (0.0%) | - | |
Postoperative pleural effusion | 10 (7.8%) | 2 (3.1%) | 0.343 | |
Postoperative stress ulcer | 1 (0.8%) | 1 (1.6%) | 1.000 | |
Surgical complications | 24 (18.8%) | 8 (12.5%) | 0.273 | |
Posthepatectomy liver failure | 2 (1.6%) | 1 (1.6%) | 1.000 | |
Postoperative abdominal infection | 3 (2.3%) | 5 (7.8%) | 0.120 | |
Postoperative bile leakage | 8 (6.3%) | 2 (3.1%) | 0.500 | |
Postoperative abdominal collection | 4 (3.1%) | 2 (3.1%) | 1.000 | |
Incision infection | 3 (2.3%) | 0 (0.0%) | 0.552 | |
Postoperative ileus | 4 (3.1%) | 0 (0.0%) | 0.303 | |
Postoperative abdominal bleeding | 5 (3.9%) | 1 (1.6%) | 0.666 | |
ICU | 5 (3.9%) | 6 (9.4%) | 0.185 | |
ICU stay (days) | 2 (1–6) | 1.5 (1–6) | 0.537 | |
Postoperative RBC transfusion | 11 (8.6%) | 7 (10.9%) | 0.599 | |
Postoperative RBC transfused (U) | 4 (2–58) | 2 (2–6) | 0.151 | |
Reoperation | 4 (3.1%) | 0 (0.0%) | 0.303 | |
Readmission | 0 (0.0%) | 3 (4.7%) | 0.036 | |
Mortality (in-hospital) | 1 (0.8%) | 0 (0.0%) | 1.000 | |
Mortality (90-day) | 1 (0.8%) | 0 (0.0%) | 1.000 | |
Recurrence | 102 (79.7%) | 43 (67.2%) | 0.058 | |
Intrahepatic recurrence | 70 (54.7%) | 34 (53.1%) | 0.838 | |
Extrahepatic recurrence | 32 (25.0%) | 9 (14.1%) | 0.081 | |
Disease-free survival | 0.269 | |||
1-year | 43.5% | 51.4% | ||
3-year | 21.2% | 30.3% | ||
5-year | 18.5% | 24.1% | ||
Overall survival | 0.401 | |||
1-year | 89.0% | 89.1% | ||
3-year | 47.8% | 57.7% | ||
5-year | 32.7% | 45.4% | ||
Cancer-specific survival | 0.163 | |||
1-year | 89.8% | 89.1% | ||
3-year | 48.2% | 61.1% | ||
5-year | 32.9% | 48.0% |