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Table 1 Risk factors for lymph node metastases by univariate analysis

From: Prognostic impact of lymph node parameters in distal cholangiocarcinoma after pancreaticoduodenectomy

Variables Lymph node metastasis group (n = 51) Control group (n = 72) p value
Age (years) 65.1 ± 10.6 64.9 ± 8.1 0.888
Leukocyte (× 109) 6.8 ± 2.6 6.8 ± 2.0 0.880
Neutrophil ratio (%) 67.6 ± 10.7 66.0 ± 10.1 0.408
ALB (g/L) 32.8 ± 5.8 35.0 ± 6.1 0.047
ALT (U/L) 73.0 (35.0, 157.7) 67.0 (33.8, 146.3) 0.904
AST (U/L) 67.0 (34.5, 121.0) 58.0 (39.3, 92.5) 0.698
TB (μmol/L) 165.6 (43.0, 246.7) 76.6 (32.2, 195.6) 0.102
DB (μmol/L) 128.8 (29.6, 205.5) 70.8 (23.7, 133.7) 0.028
GGT (U/L) 364.0 (166.0, 726.0) 386.0 (127.0, 1005.0) 0.679
CA19-9 (U/mL) 176.6 (56.5, 407.3) 36.9 (12.7, 71.6) 0.000
Tumor diameter (cm) 2.3 ± 1.1 2.1 ± 0.9 0.350
Gender (%)    0.491
 Male 28 (54.9) 44 (61.1)  
 Female 23 (45.1) 28 (38.9)  
Diabetes history (%)    0.436
 Yes 16 (31.4) 18 (25.0)  
 No 35 (68.6) 54 (75.0)  
Smoking history (%)    0.374
 Yes 18 (35.3) 20 (27.8)  
 No 33 (64.7) 52 (72.2)  
Biliary drainage history (%)    0.986
 Yes 24 (47.1) 34 (47.2)  
 No 27 (52.9) 38 (52.8)  
Differentiation (%)    0.017
 Poor 9 (17.6) 20 (27.8)  
 Moderate 20 (39.2) 38 (52.8)  
 Well 22 (43.1) 14 (19.4)  
Perineural invasion (%)    0.215
 Yes 47 (92.2) 61 (84.7)  
 No 4 (7.8) 11 (15.3)  
Portal vein system invasion (%)    0.002
 Yes 13 (25.5) 4 (5.6)  
 No 38 (74.5) 68 (94.4)  
T stage (%)    0.946
 T1 1 (2.0) 1 (1.3)  
 T2 5 (9.8) 8 (11.1)  
 T3 45 (88.2) 63 (87.5)