Table 1 Risk factors for lymph node metastases by univariate analysis
Variables | Lymph node metastasis group (n = 51) | Control group (n = 72) | p value |
|---|---|---|---|
Age (years) | 65.1 ± 10.6 | 64.9 ± 8.1 | 0.888 |
Leukocyte (× 109) | 6.8 ± 2.6 | 6.8 ± 2.0 | 0.880 |
Neutrophil ratio (%) | 67.6 ± 10.7 | 66.0 ± 10.1 | 0.408 |
ALB (g/L) | 32.8 ± 5.8 | 35.0 ± 6.1 | 0.047 |
ALT (U/L) | 73.0 (35.0, 157.7) | 67.0 (33.8, 146.3) | 0.904 |
AST (U/L) | 67.0 (34.5, 121.0) | 58.0 (39.3, 92.5) | 0.698 |
TB (μmol/L) | 165.6 (43.0, 246.7) | 76.6 (32.2, 195.6) | 0.102 |
DB (μmol/L) | 128.8 (29.6, 205.5) | 70.8 (23.7, 133.7) | 0.028 |
GGT (U/L) | 364.0 (166.0, 726.0) | 386.0 (127.0, 1005.0) | 0.679 |
CA19-9 (U/mL) | 176.6 (56.5, 407.3) | 36.9 (12.7, 71.6) | 0.000 |
Tumor diameter (cm) | 2.3 ± 1.1 | 2.1 ± 0.9 | 0.350 |
Gender (%) | 0.491 | ||
Male | 28 (54.9) | 44 (61.1) | |
Female | 23 (45.1) | 28 (38.9) | |
Diabetes history (%) | 0.436 | ||
Yes | 16 (31.4) | 18 (25.0) | |
No | 35 (68.6) | 54 (75.0) | |
Smoking history (%) | 0.374 | ||
Yes | 18 (35.3) | 20 (27.8) | |
No | 33 (64.7) | 52 (72.2) | |
Biliary drainage history (%) | 0.986 | ||
Yes | 24 (47.1) | 34 (47.2) | |
No | 27 (52.9) | 38 (52.8) | |
Differentiation (%) | 0.017 | ||
Poor | 9 (17.6) | 20 (27.8) | |
Moderate | 20 (39.2) | 38 (52.8) | |
Well | 22 (43.1) | 14 (19.4) | |
Perineural invasion (%) | 0.215 | ||
Yes | 47 (92.2) | 61 (84.7) | |
No | 4 (7.8) | 11 (15.3) | |
Portal vein system invasion (%) | 0.002 | ||
Yes | 13 (25.5) | 4 (5.6) | |
No | 38 (74.5) | 68 (94.4) | |
T stage (%) | 0.946 | ||
T1 | 1 (2.0) | 1 (1.3) | |
T2 | 5 (9.8) | 8 (11.1) | |
T3 | 45 (88.2) | 63 (87.5) |