Table 5 Show prognostic factors results of subgroup meta-analysis of pooled HR, 95% CI

The male vs. the female [16, 29,30,31, 35]

7

0.65–3.87

1.09

0.87–1.37

55.3%

Random

0.466

2017–2020

5

0.65–3.87

1.01

0.75–1.36

62.4%

Random

0.956

2013–2014

2

1.23–1.62

1.28

0.98–1.68

0.0%

Random

0.069

The older vs. the younger [14, 16, 29,30,31,32, 35, 37]

9

0.63–8.13

1.45

0.98–2.16

80.3%

Random

0.065

2017–2020

7

0.81–8.13

1.67

1.10–2.54

81.0%

Random

0.017

2013–2014

2

0.63–0.83

0.79

0.47–1.35

0.0%

Random

0.391

NF 1 vs. non–NF 1 MPNST [11, 13,14,15,16, 18, 30, 34,35,36,37, 40, 42]

13

1.00–3.54

1.56

1.35–1.79

34.1%

Fixed

0.000

2016–2020

9

1.00–3.54

1.56

1.20–2.02

52.9%

Random

0.001

2006–2014

4

1.37–1.96

1.68

1.26–2.25

0.0%

Random

0.000

Large size vs. small size [13, 14, 17, 28, 30, 31, 35,36,37, 44]

10

1.04–7.88

1.93

1.62–2.29

44.4%

Random

0.000

2017–2020

7

1.04–2.99

1.74

1.45–2.10

0.0%

Random

0.000

2007–2014

3

4.20–7.88

5.18

2.90–9.24

0.0%

Random

0.000

Deep vs. superficial to fascia [14, 15, 24, 29, 34]

5

1.79–3.16

2.09

1.52–2.89

0.0%

Fixed

0.000

2016–2020

4

1.79–3.16

2.09

1.51–2.90

0.0%

Random

0.000

2012

1

2.10

2.10

0.27–16.22

–

–

0.477

Trunk vs. extremity [15, 17, 18, 24, 34]

5

1.01–3.70

1.79

1.07–3.00

74.9%

Random

0.025

2016–2020

2

1.01–1.26

1.05

0.83–1.32

0.0%

Random

0.684

2006–2012

3

2.54–3.70

2.75

1.79–4.21

0.0%

Random

0.000

Head and neck vs. extremity [14,15,16, 18, 30, 40]

6

1.10–4.15

1.38

1.07–1.78

30.3%

Fixed

0.014

2016–2020

3

1.11–3.25

1.47

0.88–2.47

41.4%

Random

0.145

2006–2014

3

1.10–4.15

1.81

0.98–3.34

21.0%

Random

0.057

Grade II vs. Grade I [13,14,15,16, 31]

6

0.89–2.99

1.43

1.06–1.91

43.7%

Fixed

0.017

2016–2019

5

0.89–2.99

1.63

0.96–2.77

52.8%

Random

0.071

2014

1

1.85

1.85

0.80–4.26

–

–

0.151

Grade III vs. Grade I [13,14,15,16, 31]

6

0.89–35.88

3.21

1.36–7.54

86.9%

Random

0.008

2016–2019

5

0.89–35.88

3.30

1.20–9.05

88.1%

Random

0.021

2014

1

3.14

3.14

1.45–6.83

–

–

0.004

With vs. without metastases [13, 16, 31, 32, 44]

6

1.11–4.80

2.30

1.50–3.51

62.3%

Random

0.000

2019

4

1.11–3.65

2.39

1.46–3.89

63.5%

Random

0.000

2007–2014

2

1.50–4.80

2.34

0.77–7.10

63.7%

Random

0.134

R1 vs. R0 resection [13, 15, 28, 30, 37]

6

0.98–5.93

1.31

1.04–1.64

22.3%

Fixed

0.022

2016–2020

5

0.98–2.27

1.25

0.99–1.58

0.0%

Random

0.058

2014

1

5.93

5.93

1.50–23.49

–

–

0.011

R2 vs. R0 resection [13,14,15, 18, 28,29,30, 35, 37]

10

0.97–13.15

2.40

1.96–2.95

0.0%

Fixed

0.000

2016–2020

7

1.89–7.63

2.34

1.84–2.97

0.0%

Random

0.000

2006–2014

3

1.86-13.15

3.15

1.46–6.92

64.3%

Random

0.004

With vs. without chemotherapy [14, 16, 18, 30, 32, 35, 40]

7

0.38–0.99

0.70

0.59–0.83

6.3%

Fixed

0.000

2017–2020

4

0.63–0.99

0.75

0.60–0.94

28.0%

Random

0.013

2006–2014

3

0.38–0.70

0.56

0.37–0.86

0.56

Random

0.008

With vs. without radiotherapy [14,15,16, 18, 28, 30, 35]

7

0.31–0.96

0.65

0.49–0.88

50.0%

Random

0.005

2016–2020

4

0.64–0.96

0.87

0.72–1.05

0.0%

Random

0.136

2006–2014

3

0.31–0.53

0.45

0.30–0.67

0.0%

Random

0.000