Fig. 1

LncRNA NEAT1 highly expressed in OSCC cell lines and promoted proliferation and EMT but inhibited apoptosis. a Expressions of lncRNA NEAT1 in HOEC, SCC-25, TSCC1, and CAL-27 cell lines were examined with RT-qPCR with normalizing to GAPDH and the statistical test was comparing each of the OSCC cell lines to the HOEC cell line, **P < 0.05. b After suppression, levels of siNEAT1-1, siNEAT1-2, and siNC were checked by RT-qPCR with normalizing to GAPDH and the statistical test was comparing siNEAT1-1 and siNEAT1-2 to siNC, **P < 0.05. c CCK-8 was assessed to measure cell viabilities in TSCC1 cell line with siNC and siNEAT1-2 and the statistical test was comparing siNEAT1-2 to siNC, **P < 0.05. d Apoptosis rate of cells in TSCC1 cell line with transfected siNEAT1-2 and siNC were validated using flow cytometry and the statistical test was comparing siNEAT1-2 to siNC, **P < 0.05. e Expressions of E-cadherin, N-cadherin, Vimentin, and Snail were checked with RT-qPCR with normalizing to GAPDH and the statistical test was comparing E-cadherin, N-cadherin, Vimentin, and Snail in siNEAT1-2 group to E-cadherin, N-cadherin, Vimentin, and Snail in siNC group, **P < 0.05. Each experiment was repeated three times