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Table 1 GO function node list (top 3) significantly enriched by upregulated and downregulated DEGs

From: Prognostic biomarkers related to breast cancer recurrence identified based on Logit model analysis

 

Category

Term

Count

p value

Upregulation

BP

GO:0006955~immune response

67

1.270E−27

GO:0006952~defense response

45

1.130E−13

GO:0019882~antigen processing and presentation

14

9.100E−09

CC

GO:0044459~plasma membrane part

75

9.160E−08

GO:0005887~integral to plasma membrane

45

6.820E−06

GO:0005886~plasma membrane

103

7.390E−06

MF

GO:0019955~cytokine binding

10

2.910E−04

GO:0008236~serine-type peptidase activity

10

8.588E−03

GO:0017171~serine hydrolase activity

10

9.209E−03

KEGG

hsa04514:Cell adhesion molecules (CAMs)

15

9.070E−06

hsa04612:Antigen processing and presentation

12

1.040E−05

hsa04062:Chemokine signaling pathway

17

3.180E−05

Downregulation

BP

GO:0045137~development of primary sexual characteristics

5

8.024E−03

GO:0009968~negative regulation of signal transduction

6

1.340E−02

GO:0007548~sex differentiation

5

1.409E−02

CC

GO:0044456~synapse part

7

1.228E−02

GO:0045202~synapse

8

2.139E−02

GO:0005761~mitochondrial ribosome

3

3.516E−02

MF

GO:0048306~calcium-dependent protein binding

3

1.372E−02

GO:0005509~calcium ion binding

14

1.696E−02

GO:0008083~growth factor activity

5

2.078E−02

KEGG

hsa04514:Cell adhesion molecules (CAMs)

3

2.108E−02

hsa04150:mTOR signaling pathway

2

2.884E−02

hsa03018:RNA degradation

2

3.115E−02