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Table 2 Adverse events during chemotherapy

From: Long-term outcomes and safety of radical transmediastinal esophagectomy with preoperative docetaxel, cisplatin, and 5-fluorouracil combination chemotherapy for locally advanced squamous cell carcinoma of the thoracic esophagus

 

Grade 1

Grade 2

Grade 3

Grade 4

%Grade 3/4

Laboratory findings

 WBC decreased

5

0

9

2

68.8

 Neutrophil count decreased

0

1

7

8

93.8

 Anemia

7

0

0

0

0

 Hypoalbuminemia

5

11

0

0

0

 Total bilirubin increased

1

1

0

0

0

 AST increased

1

0

0

0

0

 ALT increased

2

0

0

0

0

 Hyponatremia

4

0

0

0

0

 Hypokalemia

2

0

0

0

0

 Creatinine increased

2

0

0

0

0

Objective findings

 Febrile neutropenia

5

0

31.3

 Lung infection

0

0

1

0

6.3

 Nausea

4

4

0

0

0

 Diarrhea

3

5

4

0

25.0

 Constipation

8

2

1

0

6.3

 Abdominal pain

7

0

0

0

0

 Herpes simplex reactivation

0

1

0

0

0

  1. WBC white blood cells, AST aspartate aminotransferase, ALT alanine transaminase