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Table 2 Summary of cases of tubal choriocarcinoma

From: Tubal choriocarcinoma presented as ruptured ectopic pregnancy: a case report and review of the literature

Author

Age

Clinical presentation

β hCG (mIU/ml)

Tumor size (cm)

Surgery

Chemotherapy

Outcome

Mehrotra et al. [2]

30

Abdominal pain, fever, fatigue, tachycardia, and palpable mass 1 month after first trimester abortion

326,100

14 × 16

Left-sided salpingoophrectomy

EMA-CO

No evidence of recurrence

Mundkur et al. [3]

26

Mass abdomen, pain in the lower abdomen, vomiting, loss of weight, and loss of appetite

151,545

10 × 10 × 5

Right adenexectomy with partial infracholicomentectomy

EMA-CO

No evidence of recurrence

Rettenmaier et al. [4]

32

Abdominal cramping

4759

3.5 × 1.7 × 2.8; 4.3 × 1.3 × 4.4

Left-sided partial salpingectomy

Refused chemotherapy

Refused follow-up

Karaman et al. [5]

31

Amenorrhea, left lower abdominal pain, and fatigue

29,251.4

4 × 3

Left-sided complete salpingectomy

MTX

No evidence of recurrence

Cianci et al. [6]

30

Left lower abdominal pain

24,474

8

Left-sided salpingoophrectomy

EMA-CO

No evidence of recurrence

Boynukalin et al. [7]

38

Abdominal pain and vaginal bleeding

> 15,000

None

Right-sided salpingectomy

None

None

Gálvez et al. [8]

33

Intense pain in the right iliac cavity and limited genital bleeding

142.1

3.73

Right-sided salpingectomy

VCR, ActD, MTX, LV

No evidence of recurrence

Lee et al. [9]

31

Dyspnea and blood-tinged sputum

228,300

7 × 6 × 4

Tumorectomy with left salpingectomy and infracolic omentectomy

EMA-CO

No evidence of recurrence

Butler et al. [10]

24

Vaginal bleeding, lower abdominal pain, and amenorrhea

15,000

2.6

Left-sided salpingectomy

MTX

No evidence of recurrence

Lin et al. [11]

38

Pregnancy of unknown location over 9 months following ovarian induction

267,836

5

Excision of the right ovarian cyst and the left uterine tube

MTX

No evidence of recurrence

Ibrahim et al. [12]

34

A positive urine test and respiratory distress

752,601

None

Left-sided salpingectomy and wedge resection of the broad ligament

None

Died of lung metastasis of tubal choriocarcinoma

Nakayama et al. [13]

26

Genital bleeding and a persistently high level of β hCG

9903

6.4 × 1.4

Right-sided salpingectomy

None

No evidence of recurrence

  1. EMA-CO etoposide, methotrexate, actinomycin-D, cyclophosphamide, oncovin; MTX methotrexate; ActD actinomycin-D; LV leucovorin; VCR vincristine