Table 2 Univariate analysis of 14 variables related to survival of GBC patients who underwent curative resection (n = 267)
Variable | Cutoff level | Number | Survival rates (%) | P value | |
|---|---|---|---|---|---|
3 years | 5 years | ||||
Age (years) | 0.019 | ||||
< 60 | 133 | 42.2 | 32.0 | ||
≥ 60 | 134 | 28.2 | 15.3 | ||
Sex | 0.158 | ||||
Male | 105 | 29.8 | 20.2 | ||
Female | 162 | 38.7 | 25.7 | ||
Jaundice | < 0.001 | ||||
Present | 54 | 13.0 | 1.9 | ||
Absent | 213 | 40.9 | 29.8 | ||
Associated disease | 0.654 | ||||
Present | 143 | 36.0 | 25.2 | ||
Absent | 124 | 34.5 | 22.3 | ||
Tumor location | 0.002 | ||||
Gallbladder neck | 67 | 20.3 | 9.4 | ||
Gallbladder body/fundus | 200 | 40.2 | 28.9 | ||
pT (TNM) | < 0.001 | ||||
pT1 and 2 | 25 | 83.8 | 78.6 | ||
pT3 and 4 | 242 | 30.2 | 18.0 | ||
Lymph node metastasis | < 0.001 | ||||
Negative | 134 | 52.2 | 38.9 | ||
Positive | 133 | 18.1 | 9.3 | ||
Histologic differentiation | 0.049 | ||||
Well/moderate | 224 | 27.4 | 17.4 | ||
Poor | 43 | 36.7 | 24.9 | ||
Hepatic invasion | < 0.001 | ||||
Present | 129 | 20.6 | 11.1 | ||
Absent | 138 | 48.8 | 35.6 | ||
CRAO | < 0.001 | ||||
Present | 18 | 5.6 | 0.0 | ||
Absent | 249 | 36.9 | 25.0 | ||
Combined portal vein/hepatic artery resection | 0.027 | ||||
Present | 5 | 0.0 | 0.0 | ||
Absent | 262 | 35.8 | 24.1 | ||
Intraoperative blood infusion | 0.006 | ||||
Present | 44 | 25.0 | 10.9 | ||
Absent | 223 | 37.1 | 26.5 | ||
Morbidity | 0.004 | ||||
Conservative treatment | 239 | 37.6 | 25.1 | ||
Need invasive treatment | 28 | 14.3 | 5.4 | ||
Extrahepatic bile duct resection | < 0.001 | ||||
Present | 74 | 18.3 | 8.4 | ||
Absent | 193 | 41.7 | 30.0 | ||