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Table 1 Demographic data of jaundiced (n = 54) and non-jaundiced GBC patients (n = 213)

From: Effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma with radical resection

  Jaundiced, n Non-jaundiced, n P value
Male gender 30 75 0.006
Mean age (range) 58.04 ± 10.87 (35–80) 59.21 ± 10.60 (23–83) 0.478
Postoperative hospital stay 18.31 ± 12.91 (4–85) 10.92 ± 5.66 (5–51) < 0.001
Associated gallbladder disease 0.285
  Gallstones 24 (44.4%) 116 (54.5%)  
  Gallbladder polyp 1 (1.9%) 2 (0.9%)  
  Nil 29 (53.7%) 95 (44.6%)  
Tumor location    < 0.001
  Gallbladder neck 38 (70.4) 29 (13.6)  
  Gallbladder body + fundus 16 (29.6) 184 (86.4)  
Histologic type 0.107
  Moderately + well-differentiated 51 (94.4) 182 (85.4)  
  Poorly differentiated 3 (5.6) 31 (14.6)  
Extent of liver resection < 0.001
  Major hepatectomy (> 3 segments) 4 (7.4%) 1 (0.6%)  
  Anatomical segments IV–V 20 (37.0%) 146 (68.5%)  
  Gallbladder bed 30 (55.6%) 66 (30.9%)  
Extrahepatic bile duct resection 54 (100.0%) 20(9.4%) < 0.001
Combined resection of adjacent organs 9 (16.7%) 9 (4.2%) 0.003
Hepatic invasion 29 (53.7%) 100 (46.9%) 0.446
Lymph node metastasis 39 (72.2%) 94 (44.1%) < 0.001
Vascular invasion 5(9.3%) 0 (0%) < 0.001
pT 0.004
  pT2 0 (0%) 25 (11.7%)  
  pT3 45 (83.3%) 174 (81.7%)  
  pT4 9(16.7%) 14 (6.6%)  
Intraoperative bleeding (ml) 656.48 ± 532.97 (200–3200) 329.67 ± 257.13 (200–1800) < 0.001
Operative time (min) 296.02 ± 76.91 (100–470) 211.88 ± 80.10 (100–400) < 0.001
Mortality (number of patients) 2 (3.7%) 1 (0.5%) 0.105
Morbidity (need invasive treatment) 15 (27.8%) 13 (6.1%) < 0.001
  1. Note that adjacent organs include the pancreas, duodenum, stomach, and/or colon other than the liver and extrahepatic bile duct.