Table 3 Prognostic factors of overall survival

 Location

Colon/rectum

56.0/58.0

1.03 (0.46–2.24)

0.9357

 Depth

< SS/> SS

65.6/58.9

0.93 (0.28–5.81)

0.9242

 Diff.

Diff/undiff

59.1/0

23.90 (4.58–112.20)

< 0.0001

20.87 (3.78–107.13)

0.0013

 Lymphatic invasion

−/+

66.5/53.7

0.93 (0.43–2.13)

0.9569

 Vessel invasion

−/+

59.9/56.7

1.16 (0.53–2.75)

0.7172

 LN metastasis

−/+

70.3/48.7

1.53 (0.70–3.59)

0.3019

 HIF-1α

−/+

60.4/54.6

1.21 (0.55–2.85)

0.6424

 Meta. period

Meta/syn

69.0/49.8

1.79 (0.79–4.59)

0.1826

 Tumor size (cm)

< 5/> 5

60.5/47.2

1.85 (0.81–4.04)

0.1213

 Tumor number

< 5/> 5

58.4/51.1

1.67 (0.68–3.72)

0.2231

 H class

H1/H2.3

63.8/46.0

2.22 (1.02–4.96)

0.0400

1.19 (0.41–4.31)

0.7591

 Grade

A/B.C

72.7/44.2

2.89 (1.27–7.42)

0.0119

2.37 (0.20-0.61)

0.1996

 Adjuvant therapy

−/+

68.3/54.4

1.22 (0.53–3.13)

0.6514

 Hepatectomy

Minor/major

52.6/64.7

0.68 (0.20–1.79)

0.4832

 HIF-1α

−/+

75.8/54.9

3.26 (1.24–11.17)

0.0220

2.85 (1.04–10.01)

0.0422

 CA19-9

< 100/> 100

28.2/37.5

0.73 (0.27–2.53)

0.2557

 CEA

< 10/> 10

57.4/55.1

1.45 (0.60–3.84)

0.4164