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Table 2 Clinicopathological factors according to HIF-1α expression in primary site

From: HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis

Factors

 

Low expression (n = 24)

High expression (n = 51)

p value

Primary factors

 Location

Colon/rectum

16/8

30/21

0.5130

 Depth

< SS/≥ SS

1/23

6/45

0.2601

 Diff.

Diff/undiff

23/1

48/3

0.7528

 Lymphatic invasion

−/+

10/14

19/31

0.6476

 Vessel invasion

−/+

6/18

16/35

0.5684

 LN metastasis

−/+

9/15

23/28

0.5334

Metastatic factors

 Meta. period

Meta/syn

7/17

25/26

0.1005

 Tumor size (cm)

< 5≥ 5

18/6

39/12

0.8896

 Tumor number

< 5/≥ 5

19/5

41/10

0.9018

 H class

H1/H2.3

14/10

32/19

0.7150

 Grade

A/B.C

11/13

27/24

0.5656

 Adjuvant therapy

−/+

8/16

22/29

0.4188

 Hepatectomy

Minor/major

17/7

45/6

0.1633

 CA19-9a

< 100/≥ 100

19/1

40/7

0.2196

 CEAa

< 10/≥ 10

10/10

29/18

0.3758

  1. Diff differentiated type, undiff undifferentiated type, LN lymph node, SS subserous, Meta metachronous, Syn synchronous
  2. a8 patients are not available