Fig. 8

Principal component analysis (PCA) and splicing factor correlation network. a PCA of each patient with colon adenocarcinoma (COAD) according to risk score. b Splicing correlation network in COAD. Expression of 28 survival-associated splicing factors (blue triangles) was positively (red line)/negatively (green line) correlated with the Percent Spliced In (PSI) values of 12 differentially expressed genes overlapping with alternative splicing (AS) events (DEGAS) (green dots) or adverse prognosis AS events (red dots)