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Table 5 Overall survival analysis by clinicopathologic variables and body composition factors

From: Prognostic role of pre-sarcopenia and body composition with long-term outcomes in obstructive colorectal cancer: a retrospective cohort study

Variable Analysis
Univariate Multivariable
HR [95% CI] P value HR [95% CI] P value
Sex, male 1.43 [0.75–2.74] 0.284
Age > 60 2.88 [1.37–6.04] 0.005 2.51 [1.14–5.56] 0.023
ASA (I vs II + III + IV) 2.27 [1.01–5.14] 0.048 1.99 [0.84–4.71] 0.118
Stage (II vs III) 2.78 [1.17–6.64] 0.021 2.29 [0.94–5.59] 0.069
Vascular invasion 2.14 [1.04–4.40] 0.039 1.90 [1.01–3.57] 0.030
Lymphatic invasion 1.97 [0.94–4.13] 0.074
Pre-operative CEA level > 5 1.63 [0.84–3.13] 0.147
Neutrophil lymphocyte ratio ≥ 5 0.78 [0.36–1.70] 0.529   
Differentiation (well vs moderate +poor) 0.66 [0.21–1.67] 0.322
BMI ≥ 25 0.45 [0.19–1.06] 0.069
Visceral obesity ≥ 130[33] 0.63 [0.22–1.32] 0.220
Subcutaneous fat area (cm2) > 92a 0.81 [0.43–1.51] 0.504
Abdominal circumference (cm) > 83a 0.81 [0.44–1.52] 0.817
CONUT score > 7[22] 2.27 [0.53–9.61] 0.254   
Pre-sarcopenia, men < 46.4 cm2, women < 37.5 cm 2[32] 2.38 [1.29–4.41] 0.004 1.92 [1.01–3.57] 0.047
  1. CI confidence interval, ASA American Society of Anesthesiologist physical status, BMI body mass index, CEA carcinoembryonic antigen, CONUT Controlling Nutritional Status
  2. aMedian value