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Table 5 Overall survival analysis by clinicopathologic variables and body composition factors

From: Prognostic role of pre-sarcopenia and body composition with long-term outcomes in obstructive colorectal cancer: a retrospective cohort study

Variable

Analysis

Univariate

Multivariable

HR [95% CI]

P value

HR [95% CI]

P value

Sex, male

1.43 [0.75–2.74]

0.284

–

–

Age > 60

2.88 [1.37–6.04]

0.005

2.51 [1.14–5.56]

0.023

ASA (I vs II + III + IV)

2.27 [1.01–5.14]

0.048

1.99 [0.84–4.71]

0.118

Stage (II vs III)

2.78 [1.17–6.64]

0.021

2.29 [0.94–5.59]

0.069

Vascular invasion

2.14 [1.04–4.40]

0.039

1.90 [1.01–3.57]

0.030

Lymphatic invasion

1.97 [0.94–4.13]

0.074

–

–

Pre-operative CEA level > 5

1.63 [0.84–3.13]

0.147

–

–

Neutrophil lymphocyte ratio ≥ 5

0.78 [0.36–1.70]

0.529

  

Differentiation (well vs moderate +poor)

0.66 [0.21–1.67]

0.322

–

–

BMI ≥ 25

0.45 [0.19–1.06]

0.069

–

–

Visceral obesity ≥ 130[33]

0.63 [0.22–1.32]

0.220

–

–

Subcutaneous fat area (cm2) > 92a

0.81 [0.43–1.51]

0.504

–

–

Abdominal circumference (cm) > 83a

0.81 [0.44–1.52]

0.817

–

–

CONUT score > 7[22]

2.27 [0.53–9.61]

0.254

  

Pre-sarcopenia, men < 46.4 cm2, women < 37.5 cm 2[32]

2.38 [1.29–4.41]

0.004

1.92 [1.01–3.57]

0.047

  1. CI confidence interval, ASA American Society of Anesthesiologist physical status, BMI body mass index, CEA carcinoembryonic antigen, CONUT Controlling Nutritional Status
  2. aMedian value