From: Potential prognostic value of delta-like protein 3 in small cell lung cancer: a meta-analysis
Study | Year | Country | No. of samples | Sex (male/female) | Smoking history (non/yes) | Distant metastasis (negative/positive) | Tumour stage (I-II/III-IV) | Histologic subtype | Method | Outcomes | Biomarkers | Cut-off value |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Yan et al. [20] | 2019 | China | 335 | 306/29 | 93/242 | 165/170 | 29/306 | SCLC | IHC | OS | DLL3/TTF1 | score ≥ 150 |
Xie et al. [21] | 2019 | USA | 44 | 19/25 | N/A | N/A | 19/16 | SCLC | IHC | OS | DLL3 | ≥ 50% |
Tanaka et al. [22] | 2018 | Japan | 63 | 52/11 | 3/60 | N/A | N/A | SCLC | IHC | OS | DLL3 | ≥ 50% |
Regzedmaa et al. [23] | 2019 | China | 38 | 26/12 | 12/26 | 15/23 | 16/22 | SCLC | IHC | OS | DLL3/CTLA-4/MSTN | score ≥ 13.5 |
Huang et al. [24] | 2019 | China | 72 | N/A | N/A | N/A | N/A | SCLC | IHC | OS/PFS | DLL3 | score ≥ 6 |
Furuta et al. [25] | 2019 | Japan | 93 | 72/21 | 18/75 | N/A | 82/11 | SCLC | IHC | OS | DLL3/ASCL1 | ≥ 75% |