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Table 2 Survival analysis of cervical cancer patients treated with pelvic exenteration due to cancer recurrence

From: Analysis of long-term outcomes in 44 patients following pelvic exenteration due to cervical cancer

Pelvic exenteration in cervical cancer recurrence

 

Median (months)

IQR

P value

Initial FIGO stage of the disease

 IB, IIA, and IIB (n = 13)

11.4

5.5-41.4

0.70

 IIIA and IIIB (n = 10)

16.4

3.8-17.1

 IVA and IVB (n = 9)

12.3

7.7-13.3

Type of pelvic exenteration

 Anterior (n = 6)

12.2

5.9-19.7

0.88

 Total (n = 22)

11.5

5-17.1

 Posterior (n = 4)

12.3

6.7-21.8

Survival in relationship to histopathological type of cervical cancer

 Squamous cell carcinoma (n = 17)

20.5

4.9-33.1

0.01

 Adenocarcinoma (n = 14)

10.7

5.9-13.3

Vaginal fistula

 Absent (n = 28)

11.5

4.7-15.6

0.02

 Present (n = 4)

Not reached

16.0-55.6

The need of repeated surgery

 Reoperation within 30 days (n = 6)

4.5

3.2-10.7

0.02

 No reoperation within 30 days (n = 26)

13.3

5.9-19.7

Adverse events

 Severe adverse events (n = 11)

10.4

4.1-11.3

0.03

 No severe adverse events (n = 21)

19.3

8.8-25.9

Specimen margins status

 Positive margins (n = 5)

7.7

6.6-16.5

0.09

 Negative margins (n = 27)

12.3

4.7-16.6

Lymph node metastases

 Absent (n = 26)

12.3

4.3-19.5

0.55

 Present (n = 6)

11.5

6.2-13.1

Time to recurrence

 0-12 months (n = 10)

13.3

7.7-19.3

0.31

 12-36 months (n = 14)

16.4

4.7-17.5

 Above 36 months (n = 8)

10.6

6.6-15.6

History of hysterectomy during initial treatment

 Hysterectomy performed (n = 3)

7.4

1.1-78.7*

0.78

 No hysterectomy (n = 29)

12.3

4.8-18.0

  1. IQR interquartile range, corresponds to 25th-75th percentiles
  2. *Minimal and maximal value