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Table 1 Population characteristics

From: A single-center experience with pancreatic cystic neuroendocrine tumors

Variables

All (n = 106)

C-PNETs (n = 12)

M-PNETs (n = 21)

S-PNETs (n = 73)

P value (C Vs S)

P value (C Vs M)

P value (M Vs S)

Sexe, female (%)

64 (60.4)

7 (58.3)

14 (66.7)

43 (58.9)

Ns

Ns

Ns

Weight, median [min-max]

67 [10-99]

74 [45-95]

71.50 [45-85]

64.5 [10-99]

Ns

Ns

Ns

Size (m), median [min-max]

1.7 [1.4-1.9]

1.68 [1.5-1.8]

1.7 [1.5-1.8]

1.7 [1.4-1.9]

Ns

Ns

Ns

BMI > 25%

36 (37.9)

8 (66.7)

9 (42.9)

19 (26)

0.005

Ns

Ns

Age at surgery > 60 years old (%)

47 (44.3)

3 (25)

10 (47.6)

34 (46.6)

Ns

Ns

Ns

Symptoms (%)

75 (70.8)

7 (58.3)

16 (76.2)

52 (71.2)

Ns

Ns

Ns

Functional (%)

11 (10.4)

0

2 (9.5)

9 (12.3)

Ns

Ns

Ns

MEN 1 (%)

8 (7.5)

2 (16.7)

2 (9.5)

4 (5.5)

Ns

Ns

Ns

VHL (%)

5 (4.7)

0

0

5 (6.8)

Ns

Ns

Ns

Biopsy (%)

96 (90.6)

11 (91.7)

18 (85.7)

67 (91.8)

Ns

Ns

Ns

Imaging

       

 Thoraco-abdominal CT-Scan (%)

104 (98.1)

12 (100)

20 (95.2)

72 (98.6)

Ns

Ns

Ns

 EUS with fine needle aspiration (%)

95 (89.6)

12 (100)

18 (85.7)

65 (89.0)

Ns

Ns

Ns

 Abdominal MRI (%)

57 (53.8)

6 (50)

15 (71.4)

36 (49.3)

Ns

Ns

Ns

 68Ga-DOTATATE PET/CT (%)

8 (7.6)

0 (0)

1 (4.8)

7 (9.6)

Ns

Ns

Ns

 99mTc-Octreotide SPECT/CT (%)

37 (34.9)

4 (33.3)

7 (33.3)

26 (35.6)

Ns

Ns

Ns

Preoperative diagnosis of NET (%)

82 (77.4)

4 (33.3)

13 (61.9)

65 (89)

< 0.001

Ns

0.004

Metastasis at staging (%)

24 (22.6)

0

2 (9.5)

22 (30.1)

0.027

Ns

Ns

Neo-adjuvent chemotherapy (%)

8 (7.5)

0

0

8 (11)

Ns

Ns

Ns

Adjuvent chemotherapy (%)

23 (21.7)

0

3 (14.3)

20 (27.4)

0.038

Ns

Ns

Neo-adjuvent Sandostatin analog (%)

6 (5.7)

0

1 (4.8)

5 (6.8)

Ns

Ns

Ns

  1. Abbreviations: BMI body mass index, MEN 1 multiple endocrine neoplasia type 1, VHL Von-Hippel-Lindau syndrome, CT-Scan computerized tomography scan, EUS endoscopic ultrasonography, MRI magnetic resonance imaging, PET/CT positron emission tomography scan; SPECT/CT single photon emission computed tomography; NET neuro-endocrine tumor