Type IV collagen
|
Mean IRS score
|
3.24
|
2.20
|
0.49
|
Percentage of positive cells
|
0
|
0%
|
1.8%
|
1
|
26.9%
|
54.5%
|
2
|
61.6%
|
38.2%
|
3
|
11.5%
|
5.5%
|
4
|
0%
|
0%
|
Staining intensity
|
0
|
0%
|
1.8%
|
1
|
53.8%
|
61.8%
|
2
|
38.5%
|
29.1%
|
3
|
7.7%
|
7.3%
|
Cytokeratin 20
|
Mean IRS score
|
8.16
|
7.18
|
0.91
|
Percentage of positive cells
|
0
|
0%
|
10.9%
|
1
|
19.2%
|
20.0%
|
2
|
3.8%
|
5.4%
|
3
|
61.6%
|
27.3%
|
4
|
15.4%
|
36.4%
|
Staining intensity
|
0
|
0%
|
10.9%
|
1
|
15.4%
|
9.1%
|
2
|
7.7%
|
20.0%
|
3
|
76.9%
|
60.0%
|
Epithelial membrane antigen
|
Mean IRS score
|
2.84
|
2.11
|
0.41
|
Percentage of positive cells
|
0
|
0%
|
25.5%
|
1
|
26.9%
|
32.7%
|
2
|
50.0%
|
34.5%
|
3
|
23.1%
|
7.3%
|
4
|
0%
|
0%
|
Staining intensity
|
0
|
0%
|
25.5%
|
1
|
61.5%
|
40.0%
|
2
|
38.5%
|
21.8%
|
3
|
0%
|
12.7%
|
E-cadherin
|
Mean IRS score
|
10.64
|
10.45
|
0.79
|
Percentage of positive cells
|
0
|
0%
|
0%
|
1
|
0%
|
0%
|
2
|
3.8%
|
0%
|
3
|
19.2%
|
45.5%
|
4
|
77.0%
|
54.5%
|
Staining intensity
|
0
|
0%
|
0%
|
1
|
0%
|
0%
|
2
|
15.4%
|
5.5%
|
3
|
84.6%
|
94.5%
|
B-catenin
|
Mean IRS score
|
5.92
|
3.85
|
0.82
|
Percentage of positive cells
|
0
|
7.7%
|
5.4%
|
1
|
23.1%
|
16.4%
|
2
|
15.4%
|
56.4%
|
3
|
46.1%
|
14.5%
|
4
|
7.7%
|
7.3%
|
Staining intensity
|
0
|
7.7%
|
5.5%
|
1
|
23.1%
|
32.7%
|
2
|
11.5%
|
50.9%
|
3
|
57.7%
|
10.9%
|