Table 1 Clinical and histological characteristics of patients according to the location of positive surgical margin (PSM)
Characteristics | Total | Surgical margin | p value | |||
|---|---|---|---|---|---|---|
NSM | AM | OM | MM | |||
Patients, no. (%) | 416 (100) | 284 (100) | 43 (100) | 37 (100) | 52 (100) | - |
Age, years, median (IQR) | 68 (62–72) | 67 (62–72) | 68 (63–71) | 68 (64–71) | 68 (61–75) | 0.922 |
BMI, kg/m2, median (IQR) | 24.9 (23.5–27.0) | 25.0 (23.7–27.1) | 24.7 (23.8–27.1) | 25.1 (22.9–27.0) | 24.0 (22.9–27.0) | 0.078 |
Volume, ml, median (IQR) | 24.6 (18.7–34.6) | 24.6 (18.7–36.1) | 19.5 (16.6–28.1) | 25.7 (18.1–36.3) | 26.4 (16.4–35.9) | 0.167 |
PSA, ng/ml, median (IQR) | 15.8 (8.8–29.8) | 13.1 (8.3–25.7) | 15.8 (7.3–25.6) | 26.0 (13.8–57.0) | 22.6 (14.0–55.9) | < 0.001 |
Surgical approach, no. (%) | ||||||
ORP | 152 (37) | 125 (44) | 8 (19) | 12 (32) | 7 (13) | < 0.001 |
LRP | 264 (63) | 159 (56) | 35 (81) | 25 (68) | 45 (87) | |
Gleason score, no. (%) | ||||||
< 8 | 246 (59) | 193 (68) | 25 (58) | 14 (38) | 14 (27) | < 0.001 |
≥ 8 | 170 (41) | 91 (32) | 18 (42) | 23 (62) | 38 (73) | |
pTNM, no. (%) | ||||||
T2 | 270 (65) | 187 (66) | 34 (79) | 15 (41) | 34 (65) | 0.004 |
T3 | 146 (35) | 97 (34) | 9 (21) | 22 (59) | 18 (35) | |
Perineural invasion, no. (%) | ||||||
No | 289 (69) | 213 (75) | 30 (70) | 22 (59) | 24 (46) | < 0.001 |
Yes | 127 (31) | 71 (25) | 13 (30) | 15 (41) | 28 (54) | |
BCR | ||||||
No | 322 (77) | 238 (84) | 30 (70) | 24 (65) | 30 (58) | < 0.001 |
Yes | 94 (23) | 46 (16) | 13 (30) | 13 (35) | 22 (42) | |
Follow-up time, median (IQR) | 27 (20–47) | 32 (23–44) | 23 (19–29) | 25 (17–31) | 19 (16–26) | < 0.001 |