Table 4 Univariate and multivariate analyses of overall survival (OS) related to clinical variables

NHPCC

< 0.001

 pMMR

55

92.59

74.07

64.51

1

 dMMR

120

94.95

88.97

87.25

0.48

(0.239~0.966)

0.040

Sex

0.548

 F

92

94.57

85.78

81.38

 M

83

93.81

82.55

78.7

Operation type

0.006

 Hemicolectomy

124

91.8

78.45

73.4

1

 Sub/total colectomy

51

100

98.04

96.04

0.57

(0.242~1.348)

0.201

Tumor location

< 0.001

 Right colon

89

94.25

88.36

86.01

1

 Left colon

49

97.96

91.84

89.8

1.25

(0.568~2.731)

0.584

 Rectum

37

89.19

64.86

53.51

1.42

(0.629~3.217)

0.397

Tumor histology

0.281

 Adenocarcinoma

146

95.17

83.98

79.04

 Mucinous/signet ring

25

91.67

87.5

87.5

 Unclassified

4

75

75

75

Tumor differentiation

0.276

 Well

30

100

100

92.98

 Moderate

109

93.57

81.53

76.89

 Poor

33

90.63

80.92

80.92

 Unclassified

3

100

66.67

66.67

TNM_T stage

0.255

 1

13

100

100

83.92

 2

14

92.86

92.86

92.86

 3

85

98.81

84.17

81.69

 4

61

88.52

80.33

75.41

TNM_N stage

< 0.001

 0

112

97.3

92.79

89.16

1

 1

37

97.3

88.71

82.78

1.18

(0.504~2.757)

0.704

 2

20

85

50

45

4.70

(2.063~10.713)

< 0.001

 3

4

50

–

–

7.41

(1.563~35.110)

0.012

TNM_M stage

< 0.001

 No

161

97.5

88.64

85.44

1

 Yes

14

53.85

30.77

–

5.24

(1.876~14.649)

0.002