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Table 4 Univariate and multivariate analyses of predictive factors of postoperative complications with CD IIIa and CR-POPF in the pancreaticoduodenectomy group (N = 68)

From: Frailty is a useful predictive marker of postoperative complications after pancreaticoduodenectomy

Factor Postoperative complications with CD IIIa CR-POPF
Univariate Multivariate Univariate Multivariate
p value Odds ratio 95% Cl for Exp (B) p value Odds ratio 95% Cl for Exp (B) p value Odds ratio 95% Cl for Exp (B) p value Odds ratio 95% Cl for Exp (B)
Age (years) 0.62 1.036 0.986-1.089     0.339 1.031 0.968-1.099    
Sex (female/male) 0.669 1.240 0.463-3.323     0.313 0.543 0.166-1.779    
BMI (kg/m2) 0.771 0.997 0.984-1.011     0.331 1.007 0.993-1.022    
Smoking 0.672 1.230 0.442-3.210     0.818 0.871 0.266-2.848    
Alcohol 0.410 0.378 0.037-3.828     0.999 0.000 0.000    
Disease 0.811 0.964 0.715-1.301     0.160 1.274 0.909-1.787    
Diabetes mellitus 0.209 2.114 0.657-6.801     0.437 0.526 0.104-2.661    
Antithrombotic drugs 0.210 2.041 0.669-6.225     0.729 1.262 0.338-4.707    
Operative time (min) 0.809 0.999 0.995-1.004     0.095 0.995 0.998-1.001 0.184 0.996 0.989-1.002
Blood loss (g) 0.980 1.000 0.999-1.001     0.554 1.000 0.999-1.001    
Intraoperative transfusion 0.720 0.822 0.282-2.369     0.544 0.648 0.159-2.637    
Soft pancreas 0.074 2.471 0.916-6.666 0.065 2.656 0.941-7.500 0.021 6.462 1.319-31.663 0.034 5.696 1.142-28.149
Albumin (g/l) 0.287 0.603 0.237-1.533     0.954 0.968 0.314-2.980    
Lymphocyte (× 103/μl) 0.321 1.000 1.000-1.001     0.348 1.000 1.000-1.001    
Total cholesterol (mg/dl) 0.138 0.991 0.979-1.003     0.148 0.988 0.972-1.004    
Hemoglobin (g/dl) 0.533 1.046 0.907-1.207     0.701 0.968 0.821-1.141    
PNI 0.836 1.006 0.951-1.065     0.551 1.024 0.946-1.109    
CONUT score 0.483 0.779 0.388-1.565     0.162 0.504 0.193-1.317    
Sarcopenia 0.642 1.255 0.482-3.265     0.192 2.250 0.666-7.605    
Frail 0.054 5.104 0.975-26.713 0.047 5.604 1.022-30.734 0.896 1.119 0.266-6.092    
  1. Abbreviations: BMI body mass index, CD Clavien-Dindo classification, COUNT controlling nutritional status, CR-POPF clinically relevant postoperative pancreatic fistula, PNI prognostic nutritional index