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Table 5 Cox regression (multivariable) analysis for overall and disease-free survival in the study cohort

From: Risk factors for anastomotic leakage and its impact on long-term survival in left-sided colorectal cancer surgery

   Overall survival Disease-free survival
   HR (95% CI) p HR (95% CI) p
Anastomotic leakage No 1 (reference) 1 (reference)
Yes 1.53 (1.01–2.32) 0.041 1.51 (1.05–2.19) 0.026
Stage of disease I 1 (reference) 1 (reference)
II 1.26 (0.72–2.20) 0.403 1.52 (0.93–2.48) 0.090
III 2.28 (1.38–3.78) 0.001 2.94 (1.88–4.59) 0.001
IV 5.87 (3.26–10.56) 0.001 6.04 (3.51–10.38) 0.001
Gender Male 1 (reference) 1 (reference)
Female 1.03 (0.76–1.39) 0.832 0.95 (0.73–1.23) 0.714
Age (years) ≤ 55 1 (reference) 1 (reference)
56–70 1.15 (0.71–1.85) 0.566 1.02 (0.70–1.49) 0.889
≥ 71 1.90 (1.16–3.11) 0.010 1.15 (0.76-1.73) 0.498
Comorbidities by CCI 0–5 1 (reference) 1 (reference)
≥ 6 2.48 (1.64–3.74) 0.001 2.14 (1.48–3.10) 0.001
  1. CCI Charlson comorbidity index score