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Table 2 Univariate analysis of risk factors for postoperative AL in sigmoid and rectal surgery

From: Risk factors for anastomotic leakage and its impact on long-term survival in left-sided colorectal cancer surgery

 

Sigmoid surgery

Rectal surgery

Non-AL

AL

p value

Non-AL

AL

p value

(n = 244)

(n = 13)

(n = 574)

(n = 69)

BMI

< 30

147 (96.7%)

5 (3.3%)

0.337

424 (89.8%)

48 (10.2%)

0.999

≥ 30

83 (93.3%)

6 (6.7%)

122 (89.7%)

14 (10.3%)

Gender

Female

111 (94.9%)

6 (5.1%)

0.999

280 (93.3%)

20 (6.7%)

0.002

Male

133 (95.0%)

7 (5.0%)

294 (85.7%)

49 (14.3%)

ASA

I–II

158 (98.8%)

2 (1.3%)

0.002

389 (90.5%)

41 (9.5%)

0.154

III–IV

76 (89.4%)

9 (10.6%)

158 (86.3%)

25 (13.7%)

CCI

≤ 5

172 (95.6%)

8 (4.4%)

0.538

430 (91.5%)

40 (8.5%)

0.004

> 5

72 (93.5%)

5 (6.5%)

144 (83.2%)

29 (16.8%)

Ischemic heart disease

Yes

13 (100%)

0 (0%)

0.999

26 (86.7%)

4 (13.3%)

0.551

No

231 (94.7%)

13 (5.3%)

548 (89.4%)

65 (10.6%)

Diabetes mellitus

Yes

28 (90.3%)

3 (9.7%)

0.197

54 (84.4%)

10 (15.6%)

0.200

No

216 (95.6%)

10 (4.4%)

520 (89.8%)

59 (10.2%)

History of CVD

Yes

8 (100%)

0 (0.0%)

0.999

17 (89.5%)

2 (10.5%)

0.999

No

236 (94.8%)

13 (5.2%)

557 (89.3%)

67 (10.7%)

Chronic renal failure

Yes

4 (100%)

0 (0.0%)

0.999

8 (88.9%)

1 (11.1%)

0.999

No

240 (94.9%)

13 (5.1%)

566 (89.3%)

68 (10.7%)

Neoadjuvant treatment

Yes

8 (88.9%)

1 (11.1%)

0.378

161 (88.0%)

22 (12.0%)

0.484

No

236 (95.2%)

12 (4.8%)

413 (89.8%)

47 (10.2%)

Approach of surgery

Open

71 (91.0%)

7 (9.0%)

0.069

320 (87.9%)

44 (12.1%)

0.247

MI

173 (96.6%)

6 (3.4%)

254 (91.0%)

25 (9.0%)

Anastomosis level from anal verge

≤ 5

20 (95.2%)

1 (4.8%)

0.999

155 (89.1%)

19 (10.9%)

0.137

6–12

  

235 (86.4%)

37 (13.6%)

> 12

178 (93.7%)

12 (6.3%)

81 (94.2%)

5 (5.8%)

Ileostomy

Yes

0 (0.0%)

1 (100%)

0.051

330 (88.5%)

43 (11.5%)

0.519

No

244 (95.3%)

12 (4.7%)

244 (90.4%)

26 (9.6%)

T stage

T0–T2

84 (97.7%)

2 (2.3%)

0.230

200 (93.0%)

15 (7%)

0.031

T3–T4

160 (93.6%)

11 (6.4%)

374 (87.4%)

54 (12.6%)

N stage

0

143 (96%)

6 (4.0%)

0.253

357 (91.1%)

35 (8.9%)

0.130

1

70 (97.2%)

2 (2.8%)

149 (86.6%)

23 (13.4%)

2

27 (90.0%)

3 (10%)

61 (84.7%)

11 (15.3%)

M stage

0

209 (95.9%)

9 (4.1%)

0.117

531 (89.7 %)

61 (10.3 %)

0.238

1

35 (89.7%)

4 (10.3%)

43 (84.3 %)

8 (15.7 %)

TNM stage

0

5 (100%)

0 (0.0%)

0.221

6 (85.7%)

1 (14.3%)

0.568

1

64 (97.0%)

2 (3.0%)

147 (91.9%)

13 (8.1%)

2

68 (95.8%)

3 (4.2%)

178 (89.9%)

20 (10.1%)

3

72 (96.0%)

3 (4%)

200 (88.1%)

27 (11.9%)

4

35 (87.5%)

5 (12.5%)

43 (84.3%)

8 (15.7%)

Ligation of IMA

High

189 (95.9%)

8 (4.1%)

0.165

442 (88.4%)

58 (11.6%)

0.265

Low

50 (90.9%)

5 (9.1%)

117 (92.1%)

10 (7.9%)

Simultaneous operation

Yes

20 (90.9%)

2 (9.1%)

0.308

53 (85.5%)

9 (14.5%)

0.286

No

224 (95.3%)

11 (4.7%)

521 (89.7%)

60 (10.3%)

Air-water test

Yes

121 (96.8%)

4 (3.2%)

0.255

454 (88.7%)

58 (11.3%)

0.429

No

119 (93.0%)

9 (7.0%)

116 (91.3%)

11 (8.7%)

  1. BMI body mass index, ASA American Society of Anesthesiologists classification score, CCI Charlson comorbidity index score, CVD cardiovascular disease, MI minimally invasive, IMA inferior mesenteric artery, AL anastomotic leakage