Reclassification of tumor size for solitary HBV-related hepatocellular carcinoma by minimum p value method: a large retrospective study

Liu, Hongzhi; Yang, Yuan; Chen, Chuanchun; Wang, Lei; Huang, Qizhen; Zeng, Jianxing; Lin, Kongying; Zeng, Yongyi; Guo, Pengfei; Zhou, Weiping; Liu, Jingfeng

doi:10.1186/s12957-020-01963-z

Table 3 The p values of log-rank test and HR values for OS of each trichotomy size cutoff

From: Reclassification of tumor size for solitary HBV-related hepatocellular carcinoma by minimum p value method: a large retrospective study

Cutoffs (cm)		p value of log-rank			HR (95% CI) of Cox
A	B	≤ A vs. A~B	≤ A vs. > B	A~B vs. > B	A~B vs. ≤ A	> B vs. ≤ A
1	2	0.611280	0.417322	0.000224
1	3	0.401394	0.424487	< 0.0001
1	4	0.588828	0.327959	< 0.0001
1	5	0.566227	0.277350	< 0.0001
1	6	0.545619	0.222792	< 0.0001
1	7	0.493309	0.263552	< 0.0001
1	8	0.482870	0.257788	< 0.0001
1	9	0.460243	0.289755	< 0.0001
1	10	0.444595	0.325466	< 0.0001
2	3	0.083743	< 0.0001	< 0.0001
2	4	0.103040	< 0.0001	< 0.0001
2	5	0.029683	< 0.0001	< 0.0001
2	6	0.018186	< 0.0001	< 0.0001
2	7	0.005548	< 0.0001	< 0.0001
2	8	0.002914	< 0.0001	< 0.0001
2	9	0.001960	< 0.0001	< 0.0001
2	10	0.001138	< 0.0001	< 0.0001
3	4	0.451643	< 0.0001	< 0.0001
3	5	0.028445	< 0.0001	< 0.0001
3	6	0.009799	< 0.0001	< 0.0001
3	7	0.000557	< 0.0001	< 0.0001
3	8*	< 0.0001	< 0.0001	< 0.0001	1.472 (1.208–1.793)	2.574 (2.058–3.219)
3	9*	< 0.0001	< 0.0001	< 0.0001	1.497 (1.23–1.82)	2.79^# (2.21–3.523)
3	10*	< 0.0001	< 0.0001	< 0.0001	1.542 (1.27–1.874)	2.781 (2.176–3.554)
4	5	0.000843	< 0.0001	0.001334
4	6	0.000214	< 0.0001	< 0.0001
4	7*	< 0.0001	< 0.0001	< 0.0001	1.566 (1.312–1.868)	2.405 (2.009–2.879)
4	8*	< 0.0001	< 0.0001	< 0.0001	1.63 (1.376–1.932)	2.464 (2.038–2.978)
4	9*	< 0.0001	< 0.0001	< 0.0001	1.646 (1.395–1.944)	2.67 (2.184–3.263)
4	10*	< 0.0001	< 0.0001	< 0.0001	1.702 (1.447–2.004)	2.662 (2.148–3.299)
5	6	0.074289	< 0.0001	< 0.0001
5	7	< 0.0001	< 0.0001	0.000524
5	8	< 0.0001	< 0.0001	0.001047
5	9*	< 0.0001	< 0.0001	< 0.0001	1.602 (1.352–1.9)	2.42 (2.004–2.922)
5	10	< 0.0001	< 0.0001	0.000794
6	7	< 0.0001	< 0.0001	0.381256
6	8	< 0.0001	< 0.0001	0.255359
6	9	< 0.0001	< 0.0001	0.025411
6	10	< 0.0001	< 0.0001	0.069108
7	8	0.000275	< 0.0001	0.449406
7	9	< 0.0001	< 0.0001	0.037663
7	10	< 0.0001	< 0.0001	0.109361
8	9	0.044308	< 0.0001	0.042670
8	10	< 0.0001	< 0.0001	0.166143
9	10	< 0.0001	< 0.0001	0.944208

OS overall survival, HR hazard ratio, CI confidence interval
*The p values of log-rank test for OS of size cutoff had significant statistical difference (p < 0.0001); ^# The highest HR value of Cox proportional analysis for OS

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ISSN: 1477-7819

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