Table 2 Mutation subtypes according to the primary location of GIST [7, 10, 14, 17, 19, 21, 24,25,26, 28, 39]
Genetic type | Whole GIST (%) | Gastric GIST (%) | Intestinal GIST (%) | Omental GIST (our review) |
|---|---|---|---|---|
KIT mutation | 77 | 65.2 | 79.7 | 60% (15/25) |
Exon 9 | 8 | 1.8 | 23.0 | 4% (1/25) |
Exon 11 | 67 | 61.4 | 54.0 | 56% (14/25) |
Exon 13 | 1 | 1.2 | 2.3 | ― |
Exon 17 | 1 | 0.8 | 0.4 | ― |
PDGFRA mutation | 10 | 22.9 | 1.2 | 28% (7/25) |
Exon 12 | 1 | 3.1 | 0 | 8% (2/25) |
Exon 14 | < 1 | 0.5 | 0.4 | ― |
Exon 18 (D842V) | 5 | 19.3 | 0.8 | 20% (5/25) |
Wild type | 13 | 11.9 | 19.1 | 20% (5/25) |