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Table 4 False-positive report probability values for associations between COX-2 rs689466 polymorphism and colorectal cancer risk

From: COX-2 gene rs689466 polymorphism is associated with increased risk of colorectal cancer among Caucasians: a meta-analysis

Variables

OR (95% CI)

p value

Power

Prior probability

0.25

0.1

0.01

0.001

0.0001

A vs. G

 Caucasian

1.15 (1.02, 1.29)

0.025

0.898

0.533

0.774

0.974

0.997

1.000

AA+AG vs. GG

 Caucasian

1.14 (1.00, 1.30)

0.046

0.800

0.561

0.793

0.977

0.998

1.000

AA vs. GG

 HB

1.33 (1.00, 1.78)

0.048

0.789

0.517

0.763

0.972

0.997

1.000

  1. OR odds ratio, CI confidence interval, HB hospital-based controls