Skip to main content

Table 2 The association between COX-2 rs689466 polymorphism and colorectal cancer risk under different genetic models

From: COX-2 gene rs689466 polymorphism is associated with increased risk of colorectal cancer among Caucasians: a meta-analysis

Genetic models OR (95% CI) p (OR) Model I2 (%) p (H)
Allele model (G vs. A) 1.06 (0.94, 1.19) 0.363 Random 81.7 < 0.001
Dominant model (GG + AG vs. AA) 1.08 (0.95, 1.24) 0.237 Random 75.9 < 0.001
Recessive model (GG vs. AG + AA) 1.06 (0.84, 1.32) 0.627 Random 66.8 < 0.001
Homozygous model (GG vs. AA) 1.10 (0.84, 1.44) 0.478 Random 73.5 < 0.001
Heterozygous model (AG vs. AA) 1.07 (0.95, 1.21) 0.257 Random 66.5 < 0.001
  1. OR odds ratio, CI confidence interval, p (H) p for heterogeneity