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Table 1 Characteristics of patients with CRLMs in the three age groups

From: Multidisciplinary treatment for colorectal liver metastases in elderly patients

Variable

≤ 64 years

65-74 years

≥ 75 years

p value

(n = 265)

(n = 151)

(n = 46)

Patients

    

 Age, year

56 (30-64)

68 (65-74)

80 (75-85)

 

 Sex, male, n (%)

162 (61.1)

104 (68.9)

33 (71.7)

0.163

Primary tumor

    

 Tumor differentiation, n (%)

    

  Well or moderately

244 (92.1)

134 (88.7)

41 (89.1)

0.991

  Poorly

6 (4.0)

3 (2.0)

1 (2.2)

 Node, positive, n (%)

183 (69.6)

102 (68.5)

23 (51.1)

0.056

Comorbidity

    

 Hypertension, n (%)

46 (17.6)

37 (24.5)

19 (41.3)

0.001

 Diabetes mellitus, n (%)

21 (7.9)

26 (17.2)

6 (13.0)

0.016

 CNS conditions, n (%)

7 (2.6)

8 (2.3)

4 (8.7)

0.108

 Pulmonary disease, n (%)

11 (4.2)

6 (4.0)

3 (6.5)

0.740

 Cardiovascular disease, n (%)

9 (3.4)

11 (7.3)

8 (17.4)

0.0009

Liver metastases

    

 Synchronous with primary tumor, n (%)

151 (57.0)

82 (54.3)

23 (50)

0.642

 Synchronous resection, n (%)

97 (36.6)

48 (31.8)

14 (30.4)

0.510

 Serum CEA, ng/mL

6.6 (0.5-2606)

7.4 (0.9-7828)

9.1 (1.2-3097)

0.638

 Size, cm

2.2 (0.3-19.0)

2.5 (0.2-10.5)

3.0 (1.1-10.0)

0.149

 Number

2 (1-31)

2 (1-33)

2 (1-23)

0.041

 Extrahepatic metastasis, n (%)

46 (19.3)

17 (12.5)

6 (14.3)

0.212

  1. Continuous data expressed as median (range)
  2. CRLMs colorectal cancer liver metastases; CNS central nervous system; CEA carcinoembryonic antigen