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Table 1 Characteristics of patients with CRLMs in the three age groups

From: Multidisciplinary treatment for colorectal liver metastases in elderly patients

Variable ≤ 64 years 65-74 years ≥ 75 years p value
(n = 265) (n = 151) (n = 46)
Patients     
 Age, year 56 (30-64) 68 (65-74) 80 (75-85)  
 Sex, male, n (%) 162 (61.1) 104 (68.9) 33 (71.7) 0.163
Primary tumor     
 Tumor differentiation, n (%)     
  Well or moderately 244 (92.1) 134 (88.7) 41 (89.1) 0.991
  Poorly 6 (4.0) 3 (2.0) 1 (2.2)
 Node, positive, n (%) 183 (69.6) 102 (68.5) 23 (51.1) 0.056
Comorbidity     
 Hypertension, n (%) 46 (17.6) 37 (24.5) 19 (41.3) 0.001
 Diabetes mellitus, n (%) 21 (7.9) 26 (17.2) 6 (13.0) 0.016
 CNS conditions, n (%) 7 (2.6) 8 (2.3) 4 (8.7) 0.108
 Pulmonary disease, n (%) 11 (4.2) 6 (4.0) 3 (6.5) 0.740
 Cardiovascular disease, n (%) 9 (3.4) 11 (7.3) 8 (17.4) 0.0009
Liver metastases     
 Synchronous with primary tumor, n (%) 151 (57.0) 82 (54.3) 23 (50) 0.642
 Synchronous resection, n (%) 97 (36.6) 48 (31.8) 14 (30.4) 0.510
 Serum CEA, ng/mL 6.6 (0.5-2606) 7.4 (0.9-7828) 9.1 (1.2-3097) 0.638
 Size, cm 2.2 (0.3-19.0) 2.5 (0.2-10.5) 3.0 (1.1-10.0) 0.149
 Number 2 (1-31) 2 (1-33) 2 (1-23) 0.041
 Extrahepatic metastasis, n (%) 46 (19.3) 17 (12.5) 6 (14.3) 0.212
  1. Continuous data expressed as median (range)
  2. CRLMs colorectal cancer liver metastases; CNS central nervous system; CEA carcinoembryonic antigen