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Table 3 Top five adverse events (serious) associated with TP versus IPC

From: Talc pleurodesis versus indwelling pleural catheter among patients with malignant pleural effusion: a meta-analysis of randomized controlled trials

Adverse effects

No. of studies

TP group (event/total)

IPC group (event/total)

RR (95% CI)

P value

Heterogeneity

I2 (%)

P value

Pleural infection

2

2/126

7/126

0.28 [0.06, 1.32]

0.11

0

0.54

Pain

2

1/100

3/101

0.61 [0.03, 12.92]

0.75

50

0.16

Dyspnea/breathlessness

1

2/29

0/28

4.83 [0.24, 96.42]

0.30

NA

NA

Catheter blockage

1

1/54

1/52

0.96 [0.06, 15.00]

0.98

NA

NA

Cellulitis

1

0/54

1/52

0.32 [0.01, 7.71]

0.48

NA

NA

  1. IPC indwelling pleural catheter; TP talc pleurodesis; RR risk ratio; CI confidence interval; NA not available