Skip to main content

Table 4 Cox’s proportional hazard regression analysis of OS

From: Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer

Items

Cox’s regression analysis

P value

HR

95%CI

Lower

Higher

Univariate Cox’s regression

 Katanin P60 high

0.004

1.567

1.155

2.126

 Age (> 60.0 years)

0.986

0.997

0.737

1.350

 Male

0.469

0.877

0.616

1.250

 History of smoke

0.641

1.075

0.794

1.455

 History of drink

0.646

1.074

0.791

1.460

 Hypertension

0.619

0.923

0.674

1.265

 Hyperlipidemia

0.496

0.893

0.646

1.236

 Diabetes

0.291

0.795

0.520

1.216

 Higher pathological grade

0.001

1.508

1.196

1.901

 Tumor size (> 5.0 cm)

0.008

1.499

1.109

2.026

 LYN metastasis

< 0.001

3.107

2.287

4.221

 Higher TNM stage

< 0.001

1.494

1.238

1.804

 CEA abnormal (> 5.0 ng/mL)

0.001

1.668

1.225

2.270

Forward stepwise multivariate Cox’s regression

 Katanin P60 high

0.020

1.441

1.060

1.959

 Higher pathological grade

0.009

1.386

1.084

1.774

 LYN metastasis

< 0.001

2.801

2.057

3.814

 CEA abnormal (> 5.0 ng/mL)

0.005

1.560

1.144

2.126

  1. OS overall survival, HR hazard ratio, CI confidence interval, LYN lymph node, CEA carcinoembryonic antigen