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Table 4 Cox’s proportional hazard regression analysis of OS

From: Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer

Items Cox’s regression analysis
P value HR 95%CI
Lower Higher
Univariate Cox’s regression
 Katanin P60 high 0.004 1.567 1.155 2.126
 Age (> 60.0 years) 0.986 0.997 0.737 1.350
 Male 0.469 0.877 0.616 1.250
 History of smoke 0.641 1.075 0.794 1.455
 History of drink 0.646 1.074 0.791 1.460
 Hypertension 0.619 0.923 0.674 1.265
 Hyperlipidemia 0.496 0.893 0.646 1.236
 Diabetes 0.291 0.795 0.520 1.216
 Higher pathological grade 0.001 1.508 1.196 1.901
 Tumor size (> 5.0 cm) 0.008 1.499 1.109 2.026
 LYN metastasis < 0.001 3.107 2.287 4.221
 Higher TNM stage < 0.001 1.494 1.238 1.804
 CEA abnormal (> 5.0 ng/mL) 0.001 1.668 1.225 2.270
Forward stepwise multivariate Cox’s regression
 Katanin P60 high 0.020 1.441 1.060 1.959
 Higher pathological grade 0.009 1.386 1.084 1.774
 LYN metastasis < 0.001 2.801 2.057 3.814
 CEA abnormal (> 5.0 ng/mL) 0.005 1.560 1.144 2.126
  1. OS overall survival, HR hazard ratio, CI confidence interval, LYN lymph node, CEA carcinoembryonic antigen