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Table 3 Cox’s proportional hazard regression analysis of DFS

From: Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer

Items

Cox’s regression analysis

P value

HR

95%CI

Lower

Higher

Univariate Cox’s regression

 Katanin P60 high

0.001

1.607

1.226

2.107

 Age (> 60.0 years)

0.158

1.216

0.927

1.596

 Male

0.757

1.053

0.758

1.464

 History of smoke

0.844

0.973

0.744

1.274

 History of drink

0.658

1.064

0.809

1.400

 Hypertension

0.928

0.987

0.747

1.304

 Hyperlipidemia

0.362

0.874

0.655

1.167

 Diabetes

0.126

0.740

0.503

1.088

 Higher pathological grade

0.061

1.218

0.991

1.498

 Tumor size (> 5.0 cm)

0.018

1.389

1.059

1.823

 LYN metastasis

< 0.001

2.565

1.943

3.388

 Higher TNM stage

< 0.001

1.524

1.288

1.804

 CEA abnormal (> 5.0 ng/mL)

0.011

1.420

1.084

1.860

Forward stepwise multivariate Cox’s regression

 Katanin P60 high

0.002

1.527

1.161

2.010

 LYN metastasis

< 0.001

2.395

1.809

3.169

 CEA abnormal (> 5.0 ng/mL)

0.020

1.382

1.052

1.815

  1. DFS disease-free survival, HR hazard ratio, CI confidence interval, LYN lymph node, CEA carcinoembryonic antigen