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Table 3 Cox’s proportional hazard regression analysis of DFS

From: Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer

Items Cox’s regression analysis
P value HR 95%CI
Lower Higher
Univariate Cox’s regression
 Katanin P60 high 0.001 1.607 1.226 2.107
 Age (> 60.0 years) 0.158 1.216 0.927 1.596
 Male 0.757 1.053 0.758 1.464
 History of smoke 0.844 0.973 0.744 1.274
 History of drink 0.658 1.064 0.809 1.400
 Hypertension 0.928 0.987 0.747 1.304
 Hyperlipidemia 0.362 0.874 0.655 1.167
 Diabetes 0.126 0.740 0.503 1.088
 Higher pathological grade 0.061 1.218 0.991 1.498
 Tumor size (> 5.0 cm) 0.018 1.389 1.059 1.823
 LYN metastasis < 0.001 2.565 1.943 3.388
 Higher TNM stage < 0.001 1.524 1.288 1.804
 CEA abnormal (> 5.0 ng/mL) 0.011 1.420 1.084 1.860
Forward stepwise multivariate Cox’s regression
 Katanin P60 high 0.002 1.527 1.161 2.010
 LYN metastasis < 0.001 2.395 1.809 3.169
 CEA abnormal (> 5.0 ng/mL) 0.020 1.382 1.052 1.815
  1. DFS disease-free survival, HR hazard ratio, CI confidence interval, LYN lymph node, CEA carcinoembryonic antigen