Fig. 1

Comparison of tumor growth among the four groups of mice. The tumor growth in endostar and combination groups was slow and was significantly inhibited in the combination group after the 7th day of local radiotherapy. Before radiotherapy, the tumor growth rate in the radiotherapy group was equivalent to that in the control group. After radiotherapy, the tumor growth gradually became slower, and the tumor volume in radiotherapy group was finally smaller than that in endostar and control groups. As can be seen from the curves, in the combination group of mice, the tumor growth rate was the slowest, the tumor volume was the smallest, and the antitumor effect was the most significant (p < 0.05)