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Table 4 Relationship between clinicopathological characteristics and BANCR and miR-9 expression in adjacent normal tissue (n = 31)

From: BRAFV600E mutation, BRAF-activated long non-coding RNA and miR-9 expression in papillary thyroid carcinoma, and their association with clinicopathological features

 

BANCR (n)

P value

miR-9 (n)

P value

 

> 0.01

≤ 0.01

> 0.01

≤ 0.01

Sex

  

0.063

  

0.185

 Female

1

21

 

18

4

 

 Male

3

6

 

5

4

 

Age (years)

  

0.621

  

0.123

 ≤ 45

3

15

 

11

7

 

 > 45

1

12

 

12

1

 

Tumor location

  

0.007

  

0.006

 Unilateral

4

6

 

4

6

 

 Bilateral

0

21

 

19

2

 

Tumor size (cm/mean)

2.7 ± 1.3

1.6 ± 0.8

0.031

1.7 ± 0.9

1.8 ± 1.1

0.804

Multifocality

  

0.007

  

0.006

 Single

4

6

 

4

6

 

 Multiple (≥ 2)

0

21

 

19

2

 

Extracapsular invasion

  

0.607

  

0.412

 No

1

13

 

9

5

 

 Yes

3

14

 

14

3

 

Extrathyroid extension

  

0.268

  

0.642

 No

2

21

 

16

7

 

 Yes

2

6

 

7

1

 

Hashimoto’s disease

  

0.561

  

0.298

 No

4

21

 

17

8

 

 Yes

0

6

 

6

0

 

Central LNM

  

0.295

  

0.66

 No

0

9

 

6

3

 

 Yes

4

18

 

17

5

 

Lateral LNM

  

0.268

  

0.178

 No

2

21

 

19

4

 

 Yes

2

6

 

4

4

 

TNM stage

  

0.490

  

0.640

 T1

2

15

 

12

5

 

 T2

0

6

 

4

2

 

 T3

2

6

 

7

1

 
  1. LNM lymph node metastasis, TNM tumor-node-metastasis