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Table 3 Relationships between clinicopathological characteristics of PTC patients and BRAFV600E mutation status and BANCR and miR-9 expression in carcinoma tissue (n = 51)

From: BRAFV600E mutation, BRAF-activated long non-coding RNA and miR-9 expression in papillary thyroid carcinoma, and their association with clinicopathological features

 

BRAFV600E mutation (n)

P value

BANCR (n)

P value

miR-9 (n)

P value

Yes

No

> 0.01

≤ 0.01

> 0.01

≤ 0.01

Sex

  

0.471

  

0.742

  

0.475

 Female

27

10

 

26

11

 

20

17

 

 Male

12

2

 

9

5

 

6

8

 

Age (years)

  

0.497

  

0.221

  

0.180

 ≤ 45

23

9

 

20

12

 

14

18

 

 > 45

16

3

 

15

4

 

12

7

 

Tumor location

  

< 0.001

  

0.654

  

0.645

 Unilateral

9

11

 

13

7

 

11

9

 

 Bilateral

30

1

 

22

9

 

15

16

 

Tumor size (cm/mean)

1.8 ± 0.7

1.3 ± 0.4

0.002

1.7 ± 0.8

1.5 ± 0.6

0.501

1.6 ± 0.8

1.7 ± 0.7

0.756

Multifocality

  

0.003

  

0.510

  

0.104

 Single

7

8

 

9

6

 

5

10

 

 Multiple (≥ 2)

32

4

 

26

10

 

21

15

 

Extracapsular invasion

  

0.004

  

0.036

  

0.121

 No

14

10

 

13

11

 

15

9

 

 Yes

25

2

 

22

5

 

11

16

 

Extrathyroid extension

  

0.173

  

0.694

  

0.140

 No

31

12

 

30

13

 

24

19

 

 Yes

8

0

 

5

3

 

2

6

 

Hashimoto’s disease

  

0.616

  

0.363

  

0.419

 No

35

10

 

32

13

 

24

21

 

 Yes

4

2

 

3

3

 

2

4

 

Central LNM

  

0.101

  

0.202

  

0.012

 No

12

7

 

12

6

 

14

5

 

 Yes

27

5

 

23

10

 

12

20

 

Lateral LNM

  

0.042

  

0.033

  

0.029

 No

23

11

 

20

14

 

21

13

 

 Yes

16

1

 

15

2

 

5

12

 

TNM stage

  

0.110

  

0.470

  

0.291

 T1

17

9

 

16

10

 

15

11

 

 T2

14

3

 

12

5

 

9

8

 

 T3

8

0

 

7

1

 

2

6

 
  1. BANCR BRAF-activated long non-coding RNA, LNM lymph node metastasis, TNM tumor-node-metastasis