Table 1 Details of the regulatory relationship between transcription factors and immune genes
TF | Immune gene | Cor | P value | Regulation |
|---|---|---|---|---|
E2F1 | NOX4 | − 5.63E−01 | 1.14E−06 | Negative |
INHBA | − 5.26E−01 | 3.04E−05 | Negative | |
STC1 | − 4.67E−01 | 2.17E−03 | Negative | |
VIP | − 4.71E−01 | 1.75E−03 | Negative | |
FOSL1 | INHBA | 4.67E−01 | 2.16E−03 | Positive |
STC1 | 4.67E−01 | 2.18E−03 | Positive | |
VIP | 4.57E−01 | 2.01E−06 | Positive | |
OXTR | 4.85E−01 | 7.00E−04 | Positive | |
HOXC11 | SLC10A2 | 9.34E−01 | 3.98E−10 | Positive |
KLF4 | CXCL3 | 5.15E−01 | 7.63E−05 | Positive |
NOX4 | − 4.96E−01 | 3.09E−04 | Negative | |
LEF1 | SLC10A2 | 4.87E−01 | 5.95E−04 | Positive |
CXCL3 | − 4.56E−01 | 4.22E−03 | Negative | |
NOX4 | 4.82E−01 | 8.60E−04 | Positive | |
INHBA | 4.84E−01 | 7.51E−04 | Positive | |
VIP | 4.65E−01 | 2.56E−03 | Positive | |
MYBL2 | NOX4 | − 5.45E−01 | 5.71E−06 | Negative |
INHBA | − 5.31E−01 | 2.01E−05 | Negative | |
STC1 | − 4.53E+01 | 4.94E−03 | Negative | |
VIP | − 4.58E−01 | 3.75E−03 | Negative | |
MYH11 | CXCL3 | − 4.58E−01 | 3.80E−03 | Negative |
NOX4 | 4.55E−01 | 4.44E−03 | Positive | |
CCL19 | 6.40E−01 | 1.84E−10 | Positive | |
INHBA | 4.80E−01 | 9.71E−04 | Positive | |
STC1 | 4.68E−01 | 2.04E−03 | Positive | |
VIP | 7.22E−01 | 5.91E−20 | Positive | |
SALL4 | SLC10A2 | 6.22E−01 | 1.66E−09 | Positive |
CXCL3 | − 4.84E−01 | 7.37E−04 | Negative | |
INHBA | 4.70E−01 | 1.81E−03 | Positive | |
SPIB | CCL19 | 4.77E−01 | 1.17E−03 | Positive |
TFAP2A | STC1 | 4.49E−01 | 6.26E−03 | Positive |