Fig. 5
From: Identification of six candidate genes for endometrial carcinoma by bioinformatics analysis
Genetic alterations and survival analysis of the total six hub genes in EC by cBio portal. a A visual summary of alteration across a set of EC samples (data taken from the TCGA Data Portal) based on a query of the six genes (COL1A1, IGF1, COL5A1, CXCL12, PTEN, and SPP1). Distinct genomic alterations are summarized and color-coded, presented by % changes in particular affected genes in individual tumor samples. Each row represents a gene and each column represents a tumor sample. b Overall survival and the disease-free survival rates of the EC patients with or without COL1A1, IGF1, COL5A1, CXCL12, PTEN, and SPP1 mutations. The red curves in the Kaplan-Meier plots include cases with gene alteration, and the blue curves include cases without gene alteration