Fig 3

Relationship between splenic enlargement and liver regeneration. a The relationship between splenic enlargement and liver regeneration. SP index ≥ 1.2: changes in splenic volume during chemotherapy were 1.2 or more (●, n = 16). SP index < 1.2: changes in splenic volume during chemotherapy were less than 1.2 (○, n = 27). No chemotherapy: patients received no preoperative chemotherapy before hepatectomy (▵, n = 67). There was statistical significance among these groups (SP index ≥ 1.2 vs SP index < 1.2 or no chemotherapy; p = 0.021, 0.033, respectively) defined by analyses of covariance. b The relationship between ICG-R15 and liver regeneration. ICG-R15 ≥ 10% (●, n = 40), ICG-R15 < 10% (○, n = 70). There was no significant difference in liver regeneration between the two groups (p = 0.40)