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Table 4 Factors predicting OS

From: Chaperonin containing t-complex polypeptide 1 subunit 6A correlates with lymph node metastasis, abnormal carcinoembryonic antigen and poor survival profiles in non-small cell lung carcinoma

Items Cox’s proportional hazard regression model
P value HR 95%CI
Lower Higher
Univariate Cox’s regression     
CCT6A high <0.001 1.952 1.515 2.516
Age (>60.0 years) 0.156 1.199 0.933 1.541
Male 0.657 1.069 0.797 1.432
History of smoke 0.149 0.832 0.648 1.068
History of drink 0.460 1.101 0.853 1.421
Hypertension 0.454 0.906 0.698 1.174
Hyperlipidemia 0.590 0.928 0.706 1.219
Diabetes 0.308 0.834 0.588 1.183
Poor differentiation 0.001 1.368 1.133 1.652
Tumor size (>5.0 cm) <0.001 1.605 1.248 2.064
LYN metastasis <0.001 3.081 2.385 3.979
Higher TNM stage <0.001 1.446 1.244 1.682
Abnormal CEA (>5.0 ng/mL) <0.001 1.880 1.444 2.447
Forward stepwise multivariate Cox’s regression
CCT6A high <0.001 1.779 1.378 2.298
Poor differentiation 0.003 1.360 1.113 1.663
LYN metastasis <0.001 2.825 2.183 3.656
Abnormal CEA (>5.0 ng/mL) <0.001 1.816 1.393 2.368
  1. Factors predicting OS were analyzed by univariate Cox’s proportional hazard regression models. The factors with P < 0.05 in univariate Cox’s regression were further analyzed in forward stepwise multivariate Cox’s regression. OS overall survival; HR hazard ratio; CI confidence interval; CCT6A chaperonin containing TCP1 subunit 6A; LYN lymph node; CEA carcinoembryonic antigen