Skip to main content

Table 4 Factors predicting OS

From: Chaperonin containing t-complex polypeptide 1 subunit 6A correlates with lymph node metastasis, abnormal carcinoembryonic antigen and poor survival profiles in non-small cell lung carcinoma

Items

Cox’s proportional hazard regression model

P value

HR

95%CI

Lower

Higher

Univariate Cox’s regression

    

CCT6A high

<0.001

1.952

1.515

2.516

Age (>60.0 years)

0.156

1.199

0.933

1.541

Male

0.657

1.069

0.797

1.432

History of smoke

0.149

0.832

0.648

1.068

History of drink

0.460

1.101

0.853

1.421

Hypertension

0.454

0.906

0.698

1.174

Hyperlipidemia

0.590

0.928

0.706

1.219

Diabetes

0.308

0.834

0.588

1.183

Poor differentiation

0.001

1.368

1.133

1.652

Tumor size (>5.0 cm)

<0.001

1.605

1.248

2.064

LYN metastasis

<0.001

3.081

2.385

3.979

Higher TNM stage

<0.001

1.446

1.244

1.682

Abnormal CEA (>5.0 ng/mL)

<0.001

1.880

1.444

2.447

Forward stepwise multivariate Cox’s regression

CCT6A high

<0.001

1.779

1.378

2.298

Poor differentiation

0.003

1.360

1.113

1.663

LYN metastasis

<0.001

2.825

2.183

3.656

Abnormal CEA (>5.0 ng/mL)

<0.001

1.816

1.393

2.368

  1. Factors predicting OS were analyzed by univariate Cox’s proportional hazard regression models. The factors with P < 0.05 in univariate Cox’s regression were further analyzed in forward stepwise multivariate Cox’s regression. OS overall survival; HR hazard ratio; CI confidence interval; CCT6A chaperonin containing TCP1 subunit 6A; LYN lymph node; CEA carcinoembryonic antigen