|
Items
|
Cox’s proportional hazard regression model
|
|---|
|
P value
|
HR
|
95%CI
|
|---|
|
Lower
|
Higher
|
|---|
|
Univariate Cox’s regression
| | | | |
|
CCT6A high
|
<0.001
|
1.952
|
1.515
|
2.516
|
|
Age (>60.0 years)
|
0.156
|
1.199
|
0.933
|
1.541
|
|
Male
|
0.657
|
1.069
|
0.797
|
1.432
|
|
History of smoke
|
0.149
|
0.832
|
0.648
|
1.068
|
|
History of drink
|
0.460
|
1.101
|
0.853
|
1.421
|
|
Hypertension
|
0.454
|
0.906
|
0.698
|
1.174
|
|
Hyperlipidemia
|
0.590
|
0.928
|
0.706
|
1.219
|
|
Diabetes
|
0.308
|
0.834
|
0.588
|
1.183
|
|
Poor differentiation
|
0.001
|
1.368
|
1.133
|
1.652
|
|
Tumor size (>5.0 cm)
|
<0.001
|
1.605
|
1.248
|
2.064
|
|
LYN metastasis
|
<0.001
|
3.081
|
2.385
|
3.979
|
|
Higher TNM stage
|
<0.001
|
1.446
|
1.244
|
1.682
|
|
Abnormal CEA (>5.0 ng/mL)
|
<0.001
|
1.880
|
1.444
|
2.447
|
|
Forward stepwise multivariate Cox’s regression
|
|
CCT6A high
|
<0.001
|
1.779
|
1.378
|
2.298
|
|
Poor differentiation
|
0.003
|
1.360
|
1.113
|
1.663
|
|
LYN metastasis
|
<0.001
|
2.825
|
2.183
|
3.656
|
|
Abnormal CEA (>5.0 ng/mL)
|
<0.001
|
1.816
|
1.393
|
2.368
|
- Factors predicting OS were analyzed by univariate Cox’s proportional hazard regression models. The factors with P < 0.05 in univariate Cox’s regression were further analyzed in forward stepwise multivariate Cox’s regression. OS overall survival; HR hazard ratio; CI confidence interval; CCT6A chaperonin containing TCP1 subunit 6A; LYN lymph node; CEA carcinoembryonic antigen
