|
Items
|
Cox’s proportional hazard regression model
|
|---|
|
P value
|
HR
|
95%CI
|
|---|
|
Lower
|
Higher
|
|---|
|
Univariate Cox’s regression
| | | | |
|
CCT6A high
|
<0.001
|
1.802
|
1.434
|
2.265
|
|
Age (>60.0 years)
|
0.019
|
1.314
|
1.047
|
1.649
|
|
Male
|
0.064
|
1.297
|
0.985
|
1.708
|
|
History of smoke
|
0.326
|
0.892
|
0.711
|
1.120
|
|
History of drink
|
0.347
|
1.117
|
0.887
|
1.405
|
|
Hypertension
|
0.386
|
0.902
|
0.714
|
1.139
|
|
Hyperlipidemia
|
0.823
|
0.973
|
0.762
|
1.241
|
|
Diabetes
|
0.363
|
0.864
|
0.631
|
1.183
|
|
Poor differentiation
|
0.002
|
1.306
|
1.102
|
1.548
|
|
Tumor size (>5.0 cm)
|
0.008
|
1.363
|
1.083
|
1.715
|
|
LYN metastasis
|
<0.001
|
2.383
|
1.883
|
3.016
|
|
Higher TNM stage
|
<0.001
|
1.448
|
1.265
|
1.658
|
|
Abnormal CEA (>5.0 ng/mL)
|
0.002
|
1.434
|
1.138
|
1.806
|
|
Forward stepwise multivariate Cox’s regression
|
|
CCT6A high
|
<0.001
|
1.659
|
1.318
|
2.089
|
|
Poor differentiation
|
0.006
|
1.281
|
1.073
|
1.530
|
|
LYN metastasis
|
<0.001
|
2.227
|
1.757
|
2.824
|
|
Abnormal CEA (>5.0 ng/mL)
|
0.004
|
1.405
|
1.114
|
1.772
|
- Factors predicting DFS were analyzed by univariate Cox’s proportional hazard regression models. The factors with P < 0.05 in univariate Cox’s regression were further analyzed in forward stepwise multivariate Cox’s regression. DFS disease-free survival; HR hazard ratio; CI confidence interval; CCT6A chaperonin containing TCP1 subunit 6A; LYN lymph node; CEA carcinoembryonic antigen
