|
No. of studies
|
OR/WMD (95%CI)
|
P
|
Heterogeneity
|
Effect model
|
---|
I2
|
P
|
---|
Age
|
12
|
0.19 (− 1.71, 2.09)
|
0.845
|
87.90
|
0.000
|
Random
|
Gender
|
17
|
0.83 (0.73, 0.94)
|
0.005
|
0.00
|
0.876
|
Fixed
|
BMI (kg/m2)
|
7
|
− 0.02 (− 0.24, 0.19)
|
0.828
|
0.00
|
0.587
|
Fixed
|
Tumor size (cm)
|
6
|
0.02 (− 0.09, 0.13)
|
0.767
|
31.50
|
0.200
|
Fixed
|
Operation time (min)
|
9
|
− 5.00 (− 13.53, 3.54)
|
0.251
|
76.30
|
0.000
|
Random
|
Blood loss (ml)
|
7
|
− 19.85 (− 45.14, 5.44)
|
0.124
|
74.90
|
0.001
|
Random
|
Proximal resection margin (cm)
|
4
|
− 0.47 (− 0.91, − 0.03)
|
0.038
|
74.30
|
0.009
|
Random
|
Distal resection margin (cm)
|
4
|
− 2.76 (− 4.96, − 0.57)
|
0.013
|
98.20
|
0.000
|
Random
|
Retrieved lymph nodes
|
8
|
− 1.10 (− 2.18, 0.01)
|
0.048
|
8.70
|
0.363
|
Fixed
|
Postoperative hospital stay (day)
|
8
|
0.98 (0.66, 1.29)
|
0.000
|
30.60
|
0.184
|
Fixed
|
Complications
|
12
|
0.97 (0.76, 1.25)
|
0.835
|
5.70
|
0.389
|
Fixed
|
Anastomotic leakage
|
10
|
0.49 (0.24, 0.97)
|
0.041
|
0.00
|
0.946
|
Fixed
|
Gastritis
|
8
|
0.22 (0.07, 0.74)
|
0.014
|
71.30
|
0.001
|
Random
|
Esophagitis
|
4
|
1.21 (0.56, 2.61)
|
0.621
|
37.90
|
0.185
|
Fixed
|
Bile reflux
|
6
|
0.30 (0.10, 0.89)
|
0.031
|
57.90
|
0.037
|
Random
|
Early dumping syndrome
|
4
|
0.18 (0.07, 0.44)
|
0.000
|
0.00
|
0.982
|
Fixed
|
Gallbladder stones
|
6
|
0.63 (0.38, 1.03)
|
0.063
|
14.60
|
0.320
|
Fixed
|
Gastric stasis
|
11
|
1.88 (1.23, 2.87)
|
0.003
|
38.40
|
0.093
|
Fixed
|
Gastric emptying times (50%, min)
|
3
|
8.86 (1.71, 16.00)
|
0.015
|
0.00
|
0.433
|
Fixed
|
Total protein*
|
7
|
0.39 (0.25, 0.53)
|
0.000
|
34.60
|
0.164
|
Fixed
|
Albumin*
|
7
|
0.31 (0.17, 0.44)
|
0.000
|
22.00
|
0.261
|
Fixed
|
Hemoglobin*
|
5
|
0.55 (0.39, 0.71)
|
0.000
|
0.00
|
0.576
|
Fixed
|
Body weight loss (Kg)
|
8
|
3.24 (1.79, 4.69)
|
0.000
|
65.30
|
0.005
|
Random
|
Recurrence
|
6
|
1.41 (0.68, 2.89)
|
0.355
|
0.00
|
0.932
|
Fixed
|
Overall survival rate
|
3
|
0.63 (− 0.06, 1.32)
|
0.074
|
0.00
|
0.951
|
Fixed
|
- P < 0.05 are indicated in bold
- OR odds ratio, WMD weight mean difference, CI confidence interval
- *Effect size is presented by standardized mean difference (SMD)