Outcome of interest | No. of studies | No. of patients | OR/WMD | 95% CI | P value | Heterogeneity P value | I2 |
---|---|---|---|---|---|---|---|
Primary outcomes | Â | Â | Â | Â | Â | Â | Â |
Mortality | 16 | 775/1085 | 0.91 | 0.64, 1.30 | 0.62 | 0.78 | 0 |
Morbidity | 12 | 553/897 | 0.67 | 0.53, 0.85 | 0.0009 | 0.05 | 0.44 |
Secondary outcomes | Â | Â | Â | Â | Â | Â | Â |
Hepatic insufficiency | 8 | 430/506 | 3.09 | 1.15, 8.31 | 0.03 | 0.001 | 0.71 |
Renal insufficiency | 4 | 154/129 | 1.07 | 0.40, 2.84 | 0.89 | 0.33 | 0.13 |
Intraoperative transfusion | 7 | 546/597 | 0.72 | 0.55, 0.94 | 0.02 | 0.07 | 0.49 |
Bile leak | 6 | 236/433 | 0.58 | 1.24, 1.41 | 0.04 | 0.04 | 57% |
R0 | 5 | 325/435 | 1.36 | 0.93, 1.96 | 0.11 | 0.77 | 0% |
Infection | 8 | 414/535 | 0.31 | 0.20, 0.47 | < 0.001 | 0.16 | 16% |
Cholangitis | 3 | 111/160 | 0.18 | 0.007, 0.48 | 0.0007 | 0.15 | 48% |
Intra-abdominal abscess | 5 | 147/289 | 0.48 | 0.22, 1.32 | 0.07 | 0.94 | 0% |
Intraoperative blood loss | 5 | 315/412 | 32.34 | − 375.83, 440.51 | 0.88 | < 0.001 | 99% |
Operative time | 4 | 235/294 | − 63.21 | − 156.16, 29.73 | 0.18 | < 0.001 | 90% |
Secondary laparotomy | 4 | 239/117 | 1.37 | 0.52, 3.63 | 0.53 | 0.47 | 0% |
Anastomotic leakage | 3 | 117/248 | 0.55 | 0.15, 2.10 | 0.38 | 0.64 | 0% |
Abdominal collection | 3 | 103/93 | 0.9 | 0.40, 2.00 | 0.79 | 0.82 | 0% |