Table 2 Clinicopathologic features of patients with normal mucosa or PanIN-1 and those with PanIN-2 or PanIN-3 at the PTM
Parameters | Normal mucosa and PanIN-1 (n = 57) | PanIN-2 and PanIN-3 (n = 21) | P value |
|---|---|---|---|
Median age (range) | 69 (45–85) | 69 (56–90) | 0.257 |
Sex | |||
 Male | 31 | 7 | 0.128 |
 Female | 26 | 14 | |
Tumor location | |||
 Head | 33 | 15 | 0.308 |
 Body and tail | 24 | 6 | |
Differentiation grade of PDAC | |||
 G1/G2 | 50 | 19 | 1.000 |
 G3/G4 | 7 | 2 | |
Differentiation grade of PDAC | |||
 G1 | 26 | 11 | 0.619 |
 G2/G3/G4 | 31 | 10 | |
TNM stage | |||
 I/II | 49 | 18 | 1.000 |
 III/IV | 8 | 3 | |
Tumor size | |||
 pT1/pT2 | 50 | 20 | 0.437 |
 pT3/pT4 | 7 | 1 | |
Microvascular invasion | |||
 Positive | 52 | 18 | 0.383 |
 Negative | 4 | 3 | |
 Unknown | 1 |  |  |
Lymphatic permeation | |||
 Positive | 39 | 15 | 1.000 |
 Negative | 18 | 6 | |
Perineural invasion | |||
 Positive | 47 | 15 | 0.346 |
 Negative | 10 | 6 | |
Nodal metastasis | |||
 pN0 | 22 | 9 | 0.797 |
 pN1/pN2 | 35 | 12 | |
Neoadjuvant chemotherapy | |||
 Yes | 36 | 9 | 0.127 |
 No | 21 | 12 | |
Adjuvant chemotherapy | |||
 Yes | 50 | 19 | 1.000 |
 No | 5 | 1 | |
 Unknown | 2 | 1 |  |
Postoperative radiotherapy | |||
 Yes | 2 | 2 | 0.292 |
 No | 55 | 19 | |