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Table 1 Clinicopathological characteristics of HCC

From: Prognoses, outcomes, and clinicopathological characteristics of very elderly patients with hepatocellular carcinoma who underwent hepatectomy

CharacteristicsGroup VE (n = 49)Group E (n = 363)Group Y (n = 384)p; VE vs. Ep; VE vs. Y
Epidemiology     
 Age (years old)82 (80–92)71 (65–79)57 (33–64)< 0.01< 0.01
 Sex, male to female (%)80(39):20(10)83(301):17(62)84(321):16(63)0.560.48
 HBs-Ag positive (%)6 (3)19 (69)53 (205)0.02< 0.01
 HCV-Ab positive (%)35 (17)34 (122)21 (80)0.880.02
 Both HBs-Ag and HCV-Ab positive (%)0 (0)1 (5)3 (10)0.400.25
 NBNC (%)59 (29)46 (167)23 (89)0.08< 0.01
Biochemical factors     
 Child-Pugh score5.2 ± 0.55.2 ± 0.55.2 ± 0.50.500.38
 Platelets (104/mm3)18.4 ± 6.817.5 ± 10.817.0 ± 7.60.540.20
 PA (%)94.8 ± 13.592.5 ± 14.091.4 ± 13.90.280.10
 ChE (IU/l)230 ± 68244 ± 71262 ± 900.220.01
 Albumin (g/dl)3.9 ± 0.34.0 ± 0.44.1 ± 0.50.060.04
 ICGR15 (%)15.8 ± 8.216.7 ± 9.615.8 ± 11.50.560.94
 AFP (ng/ml)5.5 (0–60,961)10.6 (0–378,718)27.5 (1–5,986,980)0.05< 0.01
 PIVKA-II (mAU/ml)198 (10–217,422)181 (8–664,680)207 (2.3–928,799)0.950.98
Tumor factors     
 Tumor size (cm)6.4 ± 3.55.7 ± 4.16.1 ± 5.20.230.66
 Multiple tumor (%)31 (15)35 (128)38 (144)0.520.34
 Differentiation, poor (%)39 (19)37 (134)46 (175)0.800.36
 PVI (%)14 (7)21 (75)34 (131)0.29< 0.01
 HVI (%)14 (7)11 (41)14 (52)0.540.88
 Fibrosis, f3/f4 (%)16 (8)40 (146)55 (213)< 0.01< 0.01
  1. VE very elderly group, E elderly group, Y young group, HBs-Ag HBs-antigen, HCV-Ab HCV-antibody, NBNC without HBV and HCV, PA prothrombin activity, ICGR15 indocyanine green retention rate at 15 min, AFP alpha-fetoprotein, PIVKA-II protein induced by vitamin K absence-II, PVI portal venous invasion, HVI hepatic venous invasion